- Max More was interviewed on cryonics and transhumanism; the transcript is at https://arjunkhemani.substack.com/p/24-max-more-cryonics-transhumanism.  
- Discussion of the first Satellogic CubeSat “Capitán Beto” (2013) and the company’s later shift away from openness.  
- Chemists compared web-based molecule sketching tools: Ketcher is usable but still loses to ChemDraw; Linux desktop alternatives suffer bit-rot and build problems.  
- docl proposed artificial nucleic-acid analogues built from polystyrene/arene rings that retain Watson–Crick hydrogen-bonding patterns, speculating on microfluidic DNA/RNA assembly and improved chemical stability; shared example structures via Discord images.  
- Philosophical debate on whether engineered biology “does justice” to natural complexity, the ethics of radical life-extension versus accepting aging, and humanity’s role in accelerating evolution.  
- fenn argued that instead of reinventing DNA we should move to highly inert storage media such as fluorinated polysiloxanes to prevent future nano-bio corruption of archives.