• MIB-626, a micro-crystalline NMN formulation, was shown in a randomized controlled trial (32 overweight/obese older adults, 1000–2000 mg/day) to produce dose-dependent increases in blood NAD⁺ levels while remaining safe and well-tolerated, whereas lower doses of standard NMN did not significantly raise NAD⁺ (PMID 35182418, SciDirect 2023 review, Springer 2022 review).

• Participants noted that bulk NMN prices have fallen from “thousands of dollars per kilogram” to ~US$1.50 per gram on mainstream supplement sites (iHerb example), with further price drops expected within three years.

• As a low-cost alternative, niacin (nicotinic acid) was highlighted; it reliably raises NAD⁺ but causes transient flushing due to platelet-mediated capillary blood flow.

• A Brain-Inspired podcast episode (#180) was shared on “connectome memory decoding,” covering recent work on reading memories from neural connectome data.

• Discussion pivoted to harvesting antimatter in space: Saturn’s magnetosphere naturally accumulates ~250 µg of antiprotons per year from ring interactions, and speculative schemes were proposed—solar-driven relativistic macron accelerators or light-pressure-propelled aerographite pellets—to boost production for future propulsion or energy storage.