• Vitamin K2 pharmacokinetics: MK-7’s lower lipophilicity causes it to accumulate inside lipoprotein particles where lipoprotein lipase cannot access it, reducing bio-availability compared with MK-4.

• Longevity researcher José Luis Cordeiro (author of “The Death of Death”) was photographed with Argentine president Javier Milei, interpreted as a sign of emerging political support for radical life-extension research.

• Ward Cunningham’s Smallest-Federated-Wiki (1997–2012) aimed at peer-to-peer page exchange and “profligate copying” to avoid centralized ownership, but lacked usable dumps and suffered from toxic-user collapse; participants debate whether communities or only data repositories can truly fork.

• DIY bio projects discussed include enzymatic DNA synthesis targeting >10 kbp at multiple bases per second on a single molecule, and RF oscillator + power-amplifier simulations for inductively-coupled plasma intended for waste incineration, bio-MEMS, and next-gen DNA synthesis hardware.

• Advanced neural audio codecs: Google Lyra (3 kbps speech) and Facebook Encodec (down to 1.5 kbps music) were compared with Codec2’s 700 bps minimum; ideas floated for accent/mood priors to cut bandwidth further.

• A lab PI described building “synthetic” human biology using adult stem cells and iPSCs to create multi-organ replicas and novel hybrid organs with enhanced or combined functions beyond natural mammalian design.

• Nobel laureates signed an open letter urging the EU to relax GMO rules for “New Genomic Techniques,” with participants noting the rebranding from “GMO” to “NGT” as political euphemism.

• A 40 MB tarball mirror of the original c2.com wiki (2015 scrape) and browsable text-browser “brow.sh” demo were shared, alongside lament that Ward Cunningham never provided database dumps, hindering true forking.

• Participants debated which historically productive figures the “e/acc” movement has recently alienated, with names like Wei Dai, davidad, and amarbles floated but no consensus reached.

• Muurkha proposed using Git’s native tree-diffing (parallel traversal of commit trees via root-hash comparison) as an efficient way to detect changed markdown files instead of thousands of filesystem calls.