- Recent FDA approval of gene therapy for sickle-cell anemia was cited as evidence that adult gene-therapy pipelines are rapidly expanding.  
- A tardigrade-derived protein (CAHS) that forms a reversible gel-like state was discussed; a *Protein Science* paper (doi:10.1002/pro.4941) and accompanying *Live Science* coverage claim it can slow cellular aging in human cell cultures.  
- The channel converged on llama.cpp as the de-facto standard for running large language models locally; users reported successful deployments on Xeon Phi, AMD RX 580 via Vulkan, and assorted NVIDIA GPUs.  
- A concise tutorial on program synthesis (“what-is-synthesis”) was recommended as a starting point for anyone building custom code-generation models.  
- A Progress Forum post arguing that individuals should actively desire a much larger human population was shared for debate.  
- A cryptic tweet from Steve Jurvetson was circulated, prompting skepticism about whether it was an April-Fools prank.