• Google’s new “Golgi” sandbox (https://golgi.sandbox.google.com/about) was highlighted as a protein-structure-prediction service, but participants noted it is likely “pretty locked down.”  
• The public AlphaFold portal at EBI (https://alphafold.ebi.ac.uk/) and the open-source OpenFold GitHub repo (https://github.com/google-deepmind/alphafold) were shared as more accessible alternatives, with confirmation that AlphaFold model weights are downloadable.  
• A request for fully open-source, ML-based protein-design tools with open model weights yielded the consensus that none yet exist at state-of-the-art quality; only “open ACRNs” (architectures) are available, and even those are often restricted.  
• FutureHouse’s “WikiCrow” chemistry LLM (https://www.futurehouse.org/wikicrow) and the associated Nature paper (https://www.nature.com/articles/s42256-024-00832-8) were introduced as recent advances in automated chemical-reasoning systems.  
• The channel spent extensive time dissecting the case of Robert McDougal, who claims his large intestine was removed without proper consent during a routine clinic visit; participants reviewed court filings (https://www.courtlistener.com/docket/68500815/united-states-v-mcdougal/) and archived Substack posts to evaluate allegations of medical malpractice versus mental-health issues.