- A new “reverse translation” peptide-sequencing protocol was highlighted: modified Edman degradation converts peptides into DNA-barcoded amino acids, which are read out by proximity-extension assays and NGS, enabling de-novo protein sequencing with single-molecule sensitivity and simultaneous detection of point mutations and post-translational modifications (pre-print: https://www.biorxiv.org/content/10.1101/2024.05.31.596913v1; tweet thread: https://twitter.com/JuliaBauman2/status/1803554167467942104).  
- An earlier USPTO patent (US 20030100000A1) using related DNA-templated chemistry was recalled as prior art for comparison.  
- A UK biohackathon was announced for October 2024; the event manifesto and sign-up page are at https://manifesto.biohackathon.xyz/.  
- Brief debate on the practicality of “holographic” data representations: one participant argued that forcing holographic encodings into classical digital readouts may be counter-productive, while another insisted that a concrete decoder is needed.  
- The channel’s longstanding “no-philosophy” moderation rule was praised as a key factor in maintaining signal-to-noise ratio for technical discussions.