- A Phase-1 small-molecule candidate targeting the sGC-cGMP pathway is being tested as a potentially lower-side-effect antidepressant; early speculation suggests it might also slow Alzheimer’s progression and act as a powerful nootropic if safety holds (link: Springer article on sGC-cGMP modulation).  
- Bunnie Huang’s “IRIS” project released new updates on using infrared microscopy to non-destructively verify that packaged silicon dies match their published specifications, a technique relevant to hardware supply-chain security and open-source chip validation (link: bunnie studios blog).  
- Discussion of an Aeon essay arguing that biology should abandon “solid-state” metaphors and instead center life-like, dynamic models; participants dismissed the piece as outdated contrarianism that merely restates the importance of epigenetics without new evidence.