- A historical note was shared about Giovanni Aldini’s 1802 experiment in which he stimulated the brain of a decapitated criminal by inserting metal wires into each ear and applying current from an early battery, illustrating early galvanic neuroscience efforts.

- Eli highlighted two recent Nature papers showing that routine vaccinations significantly reduce Alzheimer’s risk: influenza vaccination lowered all AD subtypes, and shingles vaccination produced a marked decrease in AD incidence, reinforcing the “prevention as cure” thesis.

- Discussion of public attitudes toward life-extension revealed that only 8 % of Russians and 30 % of Americans, according to recent polls, would choose indefinite life via rejuvenation therapy; participants debated whether cultural narratives about “mortality giving life meaning” or underlying depression skew these numbers.

- Alonzoc asked whether any genetic interventions are known to enhance tendon strength without the negative tendon effects seen with myostatin inhibition; jrayhawk cautioned that accelerated collagen growth can outpace organizational control, leading to structural problems.

- A request for an arXiv endorsement was fulfilled when kanzure agreed to sponsor abetusk’s preprint, illustrating the informal peer-gatekeeping still present in open-access scientific publishing.