- A new human exercise study published in EMBO reports that within 24 hours post-workout, the transcription factor MYC alone is sufficient to drive muscle hypertrophy, offering a potential molecular lever for accelerating strength gains or countering sarcopenia.  
- The paper (DOI: 10.1038/s44319-024-00299-z) provides a time-resolved atlas of >1,000 exercise-responsive genes and metabolites, mapping the first complete daily cycle of human muscle adaptation.  
- Findings suggest MYC activation could be targeted pharmacologically or via gene-therapy vectors to mimic the anabolic effects of resistance training without mechanical load, a prospect relevant to bed-ridden patients, astronauts, or longevity interventions.  
- The study employed single-nucleus RNA-seq, phospho-proteomics, and metabolomics on human vastus-lateralis biopsies, setting a methodological benchmark for integrative exercise physiology research.  
- Channel participants flagged the work as a candidate for open-source replication kits (protocols, plasmids, and analysis pipelines) to accelerate community-driven muscle-enhancement projects.