- A proposal for “modular memory engrams” was outlined: a directed-evolution program in mice that would breed successive generations for anatomically localized, transplantable memory circuits, verified by lesion-induced amnesia and optogenetic tagging, with the ultimate goal of surgically moving learned behaviors between individuals.  
- The same author suggested accelerating the concept by shifting from mammalian breeding to selection on neurotrophic bacteria, arguing that microbial generation times would permit far faster iteration of memory-encoding biological circuits.  
- lordkek__ raised a speculative biology question about gap-junction-mediated one-electron exchange between cells as a coordinated stress-response and repair mechanism, asking how chronic, low-level electron transfer might be interpreted physiologically.  
- Three recent high-impact preprints/ papers were circulated:  
  – “Ultra-wide-field, deep, adaptive two-photon microscopy” (bioRxiv 2025.06.07.658419v2) for large-scale brain imaging.  
  – “Megabase-scale human genome rearrangement with programmable bridge recombinases” (bioRxiv 2025.05.14.653916v2) enabling chromosome-scale edits.  
  – “Reprogramming site-specific retrotransposon activity to new DNA sites” (Nature 2025) for targeted transposon engineering.  
- A brief aside linked to Lifespan.io coverage of a new study that could improve cancer-vaccine design, flagged as “good news” by a participant.