- A proposal for “chemist-style” atomic-precision manufacturing was floated: use DNA-templated chemistry to iteratively add single-atom or small-molecule payloads, form covalent bonds on both sides, then cleave the DNA linker—building on David Liu’s 2013 DNA-templated non-nucleic-acid polymer synthesis and Stratos Genomics’ “xpandomer” chemistry.  
- Participants discussed extending the idea to create sequence-controlled, single-atom-wide nanowires and self-assembling semiconductor circuits, noting that existing nanowires are usually monomeric and questioning whether anyone has demonstrated hetero-atomic or sequence-programmable chains.  
- Two papers were shared on the electronic behavior of DNA origami: “Electronic Properties of DNA Origami Nanostructures Revealed by In Silico Calculations” (UCSB) and “Mapping DNA Conformations Using Single-Molecule Conductance Measurements,” highlighting DNA’s potential as a programmable scaffold for molecular electronics.  
- A long-form critique of Bitcoin’s “trustless” ideal argued that unavoidable layers of trust (compilers, hardware, libraries, undefined language behaviors) make the real goal “trust transparency” rather than absolute elimination; the concept of a “trust linter” was proposed as a lightweight alternative to full formal verification for cognitive security and supply-chain auditing.  
- A draft “trustlint” specification was posted (https://diyhpl.us/~bryan/irc/chatgpt/trustlint.txt) that would let logistics providers or software vendors emit signed trustlint files describing their assumptions, which downstream users could incorporate into their own trust graphs.  
- OpenAI’s new policy on synthetic-nucleic-acid screening (https://openai.com/index/preparing-for-future-ai-capabilities-in-biology/) was announced, prompting criticism that its ban on federal funding of foreign gain-of-function work is too narrow and leaves secret bioweapons programs untouched.  
- Palantir and Meta executives being appointed as U.S. Army colonels (reported by The Gray Zone) was cited as an example of the increasing entanglement of big-tech leadership with national-security operations.