- Sanjay John’s blog post “Genetics Über-Junk Science” is circulated as a critique of mainstream genomics claims, with a follow-up tweet thread collecting its key assertions.  
- Participants debate He Jiankui’s CCR5 embryo editing: arguments center on the choice of a non-lethal target, off-target CRISPR risks, mosaicism, unknown immune/brain effects, and the chilling precedent set by the Jesse Gelsinger death.  
- Tom Ellis clarifies the MRC-LMB “Synthetic Human Genome” (SynHG) project will use hierarchical, chromosome-scale assembly à la Sc2.0 and Syn61/Syn57 E. coli rather than the JCVI “boot-up” approach.  
- A detailed proposal to fix U.S. healthcare pricing is offered: pay providers 20 % more up-front in exchange for transparent pre-service bids, financed via capital markets and piloted through acquisition of a regional insurer/TPA.  
- Telegram founder Pavel Durov claims he has anonymously fathered 100+ children via free IVF using his sperm, promising each child an eventual ~$139 M inheritance slice; discussion touches on genetic privacy and future wealth effects.  
- Bioarxiv’s new Cloudflare gating is decried as blocking open access to preprints.  
- A Quantinuum blog post asserts “error rates low enough for real-world applications,” positioning the company to deliver scalable, fault-tolerant universal quantum computers by 2029; participants question the magnitude of the advance.  
- DIYhpluswiki suffers a brief vandalism/revert incident followed by server-side hook errors (missing sed/tail), quickly repaired.