- GitHub’s centralized “issues, PRs, discussions” are not in version control, making them hard to archive or migrate; participants note the lack of a complete exporter and debate whether Radicle’s DAG-based approach or a git-tree index (sparse-replicated) would be more robust and portable.  
- A 2025 open Protein Engineering Tournament (bit.ly/Tournament25) offers free DNA synthesis and wet-lab testing for AI-designed PETase enzymes that degrade PET plastic, with $30 k in prizes and EvolutionaryScale compute/models provided.  
- ChatGPT-o3 outlined five CRISPR-testable genetic interventions that could yield “sleep-pressure invulnerability” in mice: ADK over-expression, A₁/A₂A receptor loss-of-function, ENT1 hyper-activity, stabilized mitochondrial complex I, and PTGDS knockout.  
- Participants propose that venture-scale capital for human cloning or nanotech could be bootstrapped by creating micro-VC funds on AngelList rather than founding single startups, enabling coordination of smaller limited partners.  
- A handheld gaming console (Anbernic RG35XXSP / RG40XX-H) was turned into a pocket molecular-workstation by running the PDB Mol* viewer under XFCE and controlling 3-D protein rotation with game-pad joysticks.  
- NYPD reportedly pressured Thingiverse to block or scan for 3-D-printed “ghost gun” models, highlighting ongoing friction between open-source hardware repositories and law enforcement.