--- Log opened Fri Jul 29 00:00:01 2011
00:55 < archels> a cockroach was nibbling your toe.
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05:44 < kanzure> archels: well, tell it to stop
05:44 < foucist> cockroaches evolved with us
05:44 < foucist> they're like dogs
05:44 < foucist> co-evolution!
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06:34 < kanzure> "Arnsten said that the aging prefrontal cortex appears to accumulate excessive
06:34 < kanzure> levels of a signaling molecule called cAMP, which can open ion channels and
06:34 < kanzure> weaken prefrontal neuronal firing. Agents that either inhibited cAMP or
06:34 < kanzure> blocked cAMP-sensitive ion channels were able to restore more youthful firing
06:34 < kanzure> patterns in the aged neurons. One of the compounds that enhanced neuronal
06:34 < kanzure> firing was guanfacine, a medication that is already approved for treating
06:34 < kanzure> hypertension in adults, and prefrontal deficits in children, suggesting that
06:35 < kanzure> it may be helpful in the elderly as well."
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06:37 < Lucas_> http://www.nature.com/gt/journal/v18/n4/full/gt2010147a.html
06:37 < Lucas_> For Kanzure
06:37 < kanzure> what is it
06:42 < Lucas_> Human Artificial Chromosome vectors for gene therapy
06:42 < Lucas_> quite yummy, if I do say so myself
06:56 < Lucas_> http://www.pnas.org/content/87/6/2211.full.pdf+html?sid=b3e80d13-02c4-437f-95f7-a9032aaacb2a   "Site-specific integration by adeno-associated virus"
06:59 < Lucas_> "Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis" http://www.nature.com/nprot/journal/v5/n10/full/nprot.2010.131.html
07:44 < kanzure> weird, nature chemistry uses adobe indesign cs5 for formatting papers
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09:43 < kanzure> oscon 2011 "garage biology and diybio" http://www.youtube.com/watch?v=42aPiIwRLf0
09:43 < kanzure> unfortunately it's eri gentry
09:45 < kanzure> argh nobody cares about your life story
09:45 < kanzure> http://assets.en.oreilly.com/1/event/61/Garage%20Biology%20And%20DIYbio_%20Because%20We%20Can,%20Because%20We%20Have%20To%20Presentation.pdf
09:46 < fenn> i feel like i've been plunged into a bad translation of shadowrun
09:47 < fenn> so why aren't they using the diy version
09:47 < fenn> apparently schloendorn got funded and has a "real" lab now
09:47 < kanzure> yes
09:48 < kanzure> for a while now? since late 2009 or early 2010 i thought
09:48 < fenn> yeah
09:48 < kanzure> "the world is just not ready for people like us" oh god fuck this shit
09:48 < kanzure> why am i even associated with this person
09:49 < fenn> "1st meeting in new space" where is that?
09:50 < kanzure> uh uh.. i know this one
09:50 < kanzure> sunnyvale?
09:50 < fenn> ugh
09:50 < fenn> desolate car-infested wasteland
09:51 < fenn> i went through a trial period there and promptly fled to foggy SF
09:51 < fenn> but not before all my clothes faded in the sun
09:51 < QuantumG> argh, the day star
09:51 < fenn> srsly, that nuclear inferno is bad news
09:52 < fenn> hide your wife, hide your kids
09:52 < kanzure> ah at 13min 40sec she says it's sunnyvale
09:53 < fenn> the problem with the south bay is it's boring as fuck, and boring people don't fiddle around with biotech in their spare time
09:53 < fenn> <- bigot
09:53 < fenn> anyway i'd love to be proven wrong
09:54 < fenn> okay time to do some optics calculations
09:57 < foucist> fenn: south bay = sf ?
09:57 < fenn> south bay = sunnyvale, palo alto, mountain view
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11:21 < kanzure> wow the python argument parser libs still suck
11:21 < kanzure> i've always been a fan of optfunc (not optparse or argparse)
11:21 < kanzure> just tried out "argh"
11:21 < kanzure> argh makes you add a decorator (@arg) for each parameter to your function
11:21 < kanzure> and then makes you use a single variable for your parameters
11:21 < kanzure> optfunc at least has the decency to investigate the parameters of your function itself
11:21 < kanzure> but neither of these do tab completion for bash
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16:40 < kanzure> http://blogs.nature.com/news/2011/07/us_court_upholds_myriad_patent.html
16:40 < kanzure> "he United States Court of Appeals for the Federal Circuit says patents on genes and even on the isolation of a specific gene are okay"
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17:06 < uniqanomaly> has anyone patented composition of air yet?
17:07 < uniqanomaly> "we are so sorry sir, you cannot exploit in your body air composed like that because we have patent for it"
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17:59 < kanzure> more: http://www.patentlyo.com/patent/2011/07/federal-circuit-isolated-human-dna-molecules-are-patentable.html
18:05 < QuantumG> and once again.. would you prefer they kept their results secret?
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18:20 < QuantumG> .. whenever you're ready to have a grownup conversation about patents.
18:22 < kanzure> their results about brca1? they didn't do that
18:27 < uniqanomaly> QuantumG: wanna grownup conversation about patents
18:27 < uniqanomaly> http://en.wikipedia.org/wiki/The_Wright_brothers_patent_war
18:27 < uniqanomaly> explain this
18:27 < uniqanomaly> "In 1906 the Wrights received a patent for their method of flight control and fiercely defended it in the years afterward, suing foreign and domestic aviators and companies, especially Glenn Curtiss, in an attempt to collect licensing fees. The legal threat suppressed development of the U.S. aviation industry."
18:28 < QuantumG> yes, they were douchebags
18:28 < QuantumG> I've made the argument against the Wrights dozens of times.
18:28 < uniqanomaly> are you kidding me
18:29 < QuantumG> no.. why?
18:29 < uniqanomaly> suppressing development is the outcome of patents
18:29 < QuantumG> is this your grownup argument?
18:29 < uniqanomaly> don't rationalize that by saying Wrights were douchebags
18:29 < QuantumG> what about trade secrets.. do they suppress development?
18:30 < uniqanomaly> why you change subject to trade secrets?
18:30 < QuantumG> which do you want? secrecy or a functioning patent system?  you can't have it both ways..
18:30 < QuantumG> if your answer is that you want neither then you're not having a grownup conversation.
18:32 < uniqanomaly> of course, there is no secrecy right now, everyone makes everything public by patent system
18:33 < QuantumG> you just can't have a grownup argument can you?
18:33 < QuantumG> "all patents are bad" is just ignorance
18:34 < QuantumG> similarly for all trade secrets.
18:34 < QuantumG> it's almost a zero-sum between the two to get the maximum benefits
18:35 < uniqanomaly> of course if you are explaining suppressed development of whole industry by someone being a douchebag, I just can't argue with you
18:35 < QuantumG> but hey, go back to living in your little black and white world.. it'll maximize your feelings of moral superiority.  Buy a Mac while you're out.
18:36 < uniqanomaly> I have nothing left to say to you
18:36 < QuantumG> that's cause you're a fucking child
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22:34 < kanzure> glow in the dark dogs in korea http://www.dreamdogs.co.uk/glow-in-the-dark-dogs-cloned-by-scientists-1166.html
--- Log closed Sat Jul 30 00:00:03 2011