--- Log opened Thu Nov 21 00:00:31 2013
00:08 < Qfwfq|work> paperbot: http://dx.doi.org/10.1016%2F0012-365X%2894%2990019-1
00:08 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/afbf5d08fbab9d23e41ac1ecdcb3c61a.txt
00:37 < nmz787> next-gen breast implants: http://ww2.biol.sc.edu/~bergerlab/599%20PAPERS/pdfs/shackleton%202006.pdf
00:38 < nmz787> Generation of a functional mammary gland from a
00:38 < nmz787> single stem cell
00:39 < nmz787> how the hell would you even think of going about engineering a cow to produce the milk of a seal
00:41 < nmz787> get transcriptomes for a bunch of low-fat and high-fat populations of cow and seal.... find which genes were varying, then swap the seal set into the cow... but that wouldn't impact development
00:41 < nmz787> unless you time-sampled the mRNA too maybe
00:43 < nmz787> you might need an end-point measurement to be based on something that would corellate to a difference in anatomy, maybe viscosity?
00:45 < nmz787> "Moose milk has the consistency of thick cream and has the odor of fresh bovine milk"  (10% fat)
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08:23 < kanzure> "Mikhail Kazakov from OpenCascade SAS just announced at the Salome User's Day that next OCCT version will be LGPL"
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09:19 < juri_> Interesting.
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12:20 < EnLilaSko> paperbot: http://www.sciencedirect.com/science/article/pii/S0304394013004370
12:20 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/3ef9e4f0d2e739d69575ae60748d3b57.txt
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13:05 < delinquentme> paperbot, http://adsabs.harvard.edu/abs/2011TRACE..26..371S
13:06 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/ab06cfd9608f1aaa768ff8a9c583b0ff.txt
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13:44 < superkuh> paperbot: http://www.cell.com/fulltext/S0092-8674(13)01360-3
13:44 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/eaa8588c6fd0cf54dc0a4bc3a85ce4d1.txt
13:45 < superkuh> paperbot: http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=CELLPRESS&_urlversion=4&_method=citationSearch&_version=1&_piikey=S0092867413013603&md5=1372a5392a55ba9fcde0013ce8caced6
13:45 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/1e48aabe5b37c65037380b72f45bd07f.txt
13:46 < superkuh> paperbot: http://www.sciencedirect.com/science/article/pii/S0092867413013603/pdfft?md5=5727a579ed38b46c183779f13c7afeda&pid=1-s2.0-S0092867413013603-main.pdf
13:46 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/1eb9a1ba1b00faa5b134c25ecf0c527d.pdf
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13:47 < kanzure> pdfcoin
13:48 < eudoxia> you mine it by freeing papers from paywalls?
13:49 < kanzure> i dunno. probably something about doi numbers.
13:54 < nmz787> that would be cool
13:56 < nmz787> superkuh: still need those papers?
13:58 < superkuh> I got them.
13:58 < superkuh> Through paperbot. All requests were 1 paper.
13:59 < superkuh> Just had to dig for the correct URL to proceed to the next stage a couple times.
13:59 < kanzure> eudoxia: i don't think it would work
14:03 < nmz787> superkuh: so I've heard of COX-2 before, but can't place what it's importance is... they sell inhibitors as common drugs
14:04 < superkuh> Ibuprofen.
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14:05 < nmz787> hmm, which I don't take often at all, maybe once every year or two
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14:06 < superkuh> The OTC COX inhibitors are actually non-specific to COX-1 and COX-2. The former being important for the mucosal lining of the stomach. Thus the suggest to take them with food.
14:07 < superkuh> In this paper they seem to use one of the later generation COX-2 specifics.
14:07 < superkuh> (wherein the first gens had bad heart side effects)
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14:11 < nmz787> the wiki article on retinal detachment said THC could exacerbate... which seems contrary to all the non-scientific buzz about it being good for glaucoma (which I haven't actually found solid evidence supporting that it actually does help the condition)
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14:18 < superkuh> Yes. The eye specific interactions have worried me.
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15:19 < nmz787> http://transova.com/our-services/genetic-preservation-cloning.php
15:19 < nmz787> http://www.viagen.com/our-services/cloning.php
15:20 < nmz787> "To clone an animal, ViaGen needs a sample of the animals genes, in the form of an ear punch or small biopsy sample. ViaGen provides a biopsy kit and a shipping container for transport of the biopsy sample to our lab."
15:20 < nmz787> "At our lab we culture the animals cells, then transfer DNA from those cells into eggs from which we have removed the genetic material. We grow the resulting embryos in an incubator for several days, then transfer them to our recipient females using a traditional embryo transfer process. After a normal gestation period, the cloned calves, piglets, or foals are born."
15:20 < nmz787> "Calves are picked up at approximately seven months of age, and foals at 60 days of age. With pigs, pregnant gilts are picked up at 60 days of pregnancy.  All cloned animals are subjected to DNA testing to confirm their identities, and to veterinary examinations to confirm their health status."
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15:33 < phillyj> oo, lots of ppl
15:33 < phillyj> hi all
15:34 < kanzure> phillyj: hi
15:34 < nmz787> hi
15:34 < nmz787> long-time!
15:34 < phillyj> yea
15:35 < phillyj> nmz787: you're on the west coast now?
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15:39 < nmz787> yeah
15:39 < nmz787> Oregon is great, naturally lush, so great bio-wise
15:40 < nmz787> no biotech or bioinformatics work though
15:40 < nmz787> some cancer and medical device companies, but nothing interesting anyway
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15:45 < nmz787> phillyj: what have you been up to?
15:45 < phillyj> usual, working at the same place
15:46 < phillyj> get a trickle of projects, cloning and such
15:47 < phillyj> one of the bigger biotechs in my building went under
15:48 < phillyj> they're selliing off their equipment
15:48 < phillyj> not sure if the boss will get anything
15:48 < phillyj> hope there's some cheap stuff
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15:51 < kanzure> phillyj: what equipment is available? do you have storage?
15:52 < phillyj> lots of stuff, centrifuges, freezers
15:52 < phillyj> i have to get the list
15:52 < phillyj> storage space meaning?
15:52 < kanzure> if you can get a picture of the list or type up the actual list, then i'd like to see it
15:52 < kanzure> meaning if i buy some of it, can you store it or arrange for it to be moved off of their location
15:53 < phillyj> i'll have to ask them about it
15:53 < phillyj> but i guess they'd be happy if you buy stuff
15:54 < phillyj> i'm guessing its pretty new equipment because they moved in early this year
15:56 < phillyj> kanzure: there is some space in my lab, it's not too big though and I am not sure if the landlord will let me leave stuff outside the lab for too long
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15:57 < phillyj> kanzure: how interested are you?
15:57 < kanzure> 5-10%
15:58 < phillyj> depending on the equipment? Im in PA btw
16:00 < nmz787> heading to pittsburgh in the next 2 weeks phillyj ?
16:00 < phillyj> nmz787: what?
16:00 < nmz787> are youheading to pittsburgh in the next 2 weeks?
16:00 < phillyj> no
16:00 < phillyj> why>
16:01 < phillyj> ?
16:01 < nmz787> I am :P
16:01 < nmz787> too far apart too just come hang out in philly
16:01 < nmz787> or vice versa
16:01 < nmz787> unless you had plans already
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16:04 < nmz787> phillyj: do you just do single-cell organism cloning?
16:05 < nmz787> err, you mean cloning cloning, not SCNT
16:05 < nmz787> right?
16:05 < phillyj> o
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16:05 < phillyj> cloning cloning
16:05 < phillyj> lol
16:06 < phillyj> sry
16:06 < nmz787> I was just looking at this http://www.viagen.com/our-services/cloning.php
16:07 < phillyj> yea, we do most basic molecular bio stuff
16:07 < phillyj> lots of plasmid construction, mutagenesis
16:07 < phillyj> or qpcr work if it comes our way
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16:15 < phillyj> kanzure: sent you the equipment list
16:17 < juri_> i don't suppose anyone here is set up to produce DLC via the hot wire method here?
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16:18 < kanzure> phillyj: neato, thanks
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16:36 < phillyj> kanzure: did you see anything interesting in the list?
16:37 < kanzure> diode array or refractometer might be interesting
16:37 < phillyj> they're not big equipment, right?
16:38 < kanzure> i don't think there's anything on this list i really really want
16:38 < kanzure> is "TMTC" an abbreviation of "too many to count"?
16:38 < kanzure> "Freezer -40C TMTC" ?
16:38 < phillyj> thats what i think
16:39 < phillyj> no
16:39 < phillyj> theres 1 -40
16:39 < phillyj> u went cross-eyed
16:40 < kanzure> damn
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16:45 < phillyj> i might get the gloves, need to order more anyway
16:47 < kanzure> that sounds exciting
16:47 < phillyj> lol
16:47 < phillyj> money is tight
16:47 < phillyj> can only get essentials
16:47 < kanzure> nah it's cool, protection for employees is BS anyway
16:47 < phillyj> lollol
16:47 < kanzure> and protection for their projects
16:48 < kanzure> "more RNAses from skin contact? sure why not"
16:49 < phillyj> that company was a big deal, but I heard they had "money mismanagement" at the highest level
16:49 < phillyj> one monday, the parking lot it empty; they just packed up over the weekend
16:50 < kanzure> definitely the preferred method of biological waste disposal
16:51 < phillyj> 1 to 5 mil in revenue with up to 50 employees
16:51 < phillyj> the lab folks all probably got laid off
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19:39 < kanzure> "Almost sounds like it would be worth having some sort of software keep their eyes open for CryptoLocker and grab the AES key, if possible, proactively."
19:40 < kanzure> (or just detect cryptolocker in the first place)
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20:05 < kanzure> silk road timeline http://antilop.cc/sr/
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22:00 < kanzure> libgen asking for funding: http://genofond.org/viewtopic.php?f=8&t=7061
22:01 < kanzure> "The six months have expired and the time has come again to renew the seedbox lease to keep on distributing Library Genesis via torrents. The parameters are the same as before: 3TB x 4 , speed 100-800 Mbps.
22:01 < kanzure> 1) the rent cost of the current configuration for six months amounts to $ 950.
22:01 < kanzure> 2) the disc space ended at torrent 980 000 and a hardware upgrade is currently contemplated, configurations and prices are being negotiated.
22:01 < kanzure> 3) the primary server of Library Genesis is to be upgraded as well. We are considering to take OCZ RevoDrive 3 X2 240G (for database) + several HDD to 4 TB for approximately $ 1000.
22:01 < kanzure> geeze this is actually cheap
22:01 < kanzure> "We accept: PayPal, YandexMoney, Webmoney, Bitcoin (link on the main page)"
22:02 < kanzure> bitcoin donations have amounted to only 0.0222 wtf
22:05 < kanzure> their bitcoin address is 1ENFY4h7ntGZbqwcwpQtXVFJrPnfXRHQLe
22:07 < kanzure> http://blockchain.info/address/1ENFY4h7ntGZbqwcwpQtXVFJrPnfXRHQLe "total received: 0.98889322 final balance: 0.48879322"
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--- Log closed Fri Nov 22 00:00:32 2013