--- Log opened Mon Jun 29 00:00:55 2015
00:01 -!- ebowden [~ebowden@2001:8003:1011:3f01:f88b:11cd:9da6:d276] has quit [Remote host closed the connection]
00:03 -!- ebowden [~ebowden@101.177.247.250] has joined ##hplusroadmap
00:04 -!- ant4t [~s3an@50.141.77.161] has quit [Ping timeout: 276 seconds]
00:12 -!- Beatzebub_ [~beatzebub@d172-218-176-59.bchsia.telus.net] has joined ##hplusroadmap
00:12 -!- Beatzebub [~beatzebub@d172-218-176-59.bchsia.telus.net] has quit [Ping timeout: 264 seconds]
00:17 -!- Porb [~Porbus@c110-22-139-137.mckinn4.vic.optusnet.com.au] has joined ##hplusroadmap
00:19 -!- FourFire [~FourFire@146-135-11.connect.netcom.no] has quit [Ping timeout: 256 seconds]
00:24 -!- knobuddy [~Warv@unaffiliated/knobuddy] has quit [Remote host closed the connection]
00:24 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 244 seconds]
00:27 -!- ant4t [~s3an@50.141.78.152] has joined ##hplusroadmap
00:33 -!- erasmus [~esb@unaffiliated/erasmus] has quit [Quit: Namaste	]
00:33 -!- FourFire [~FourFire@33-5-11.connect.netcom.no] has joined ##hplusroadmap
00:37 -!- QuadIngi [~FourFire@77.40.154.178] has joined ##hplusroadmap
00:38 -!- FourFire [~FourFire@33-5-11.connect.netcom.no] has quit [Ping timeout: 256 seconds]
00:40 -!- QuadIngi is now known as FourFire
00:42 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap
00:43 -!- FourFire [~FourFire@77.40.154.178] has quit [Read error: Connection reset by peer]
01:05 -!- sheena [~home@S0106c8be196316d1.ok.shawcable.net] has quit [Ping timeout: 248 seconds]
01:07 -!- ant4t [~s3an@50.141.78.152] has quit [Ping timeout: 255 seconds]
01:31 -!- Acty [uid89656@gateway/web/irccloud.com/x-rrqfvwdmnzqteurb] has quit [Quit: Connection closed for inactivity]
01:44 -!- Porb [~Porbus@c110-22-139-137.mckinn4.vic.optusnet.com.au] has quit [Quit: Leaving]
01:45 -!- Porb [~Porbus@c110-22-139-137.mckinn4.vic.optusnet.com.au] has joined ##hplusroadmap
01:48 -!- Acty [uid89656@gateway/web/irccloud.com/x-mgwyqalbzgyikndn] has joined ##hplusroadmap
01:56 -!- xrr [~xrr@gprs-inet-183-94.elisa.ee] has joined ##hplusroadmap
02:26 -!- zadock [~outsider@81.180.210.87] has joined ##hplusroadmap
02:51 -!- xrr [~xrr@gprs-inet-183-94.elisa.ee] has quit [Quit: Leaving]
03:55 -!- xrr [~xrr@gprs-inet-183-94.elisa.ee] has joined ##hplusroadmap
04:02 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap
04:08 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-bwkrsomwcnccpdrs] has quit [Quit: Connection closed for inactivity]
04:16 -!- zadock [~outsider@81.180.210.87] has quit [Quit: Leaving]
04:49 -!- punsieve [~drandomtu@cpe-66-68-66-8.austin.res.rr.com] has quit [Ping timeout: 255 seconds]
05:12 -!- Madplatypus [uid19957@gateway/web/irccloud.com/x-llcvfwvzzcleqzew] has quit [Quit: Connection closed for inactivity]
05:23 -!- eudoxia [~eudoxia@r167-57-127-242.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap
05:42 -!- TheBlight [~TheBlight@gatekeeper.bbp.ch] has joined ##hplusroadmap
05:42 < kanzure> .title http://www.nature.com/nrmicro/journal/v8/n7/abs/nrmicro2392.html
05:42 < yoleaux> Where microbiology meets microengineering: design and applications of reporter bacteria : Abstract : Nature Reviews Microbiology
05:42 < kanzure> .title http://www.nature.com/nrmicro/journal/v8/n3/abs/nrmicro2262.html
05:42 < yoleaux> A complex journey: transmission of microbial symbionts : Abstract : Nature Reviews Microbiology
05:44 < kanzure> .title http://www.nature.com/nrmicro/journal/v11/n2/abs/nrmicro2937.html
05:44 < yoleaux> Bacteriocins [mdash] a viable alternative to antibiotics? : Abstract : Nature Reviews Microbiology
05:45 < kanzure> "legumes punish nonperforming nitrogen-fixing bacteria"
05:45 < kanzure> .title http://onlinelibrary.wiley.com/doi/10.1111/j.1420-9101.2010.02114.x/full
05:45 < yoleaux> The evolution of mutualism - LEIGH Jr - 2010 - Journal of Evolutionary Biology - Wiley Online Library
05:45 < kanzure> .title http://onlinelibrary.wiley.com/doi/10.1111/j.1420-9101.2010.02084.x/full
05:45 < yoleaux> The danger of applying the breeder's equation in observational studies of natural populations - MORRISSEY - 2010 - Journal of Evolutionary Biology - Wiley Online Library
05:48 < kanzure> .title http://onlinelibrary.wiley.com/doi/10.1111/j.1558-5646.2010.01025.x/abstract
05:48 < yoleaux> EARLY BURSTS OF BODY SIZE AND SHAPE EVOLUTION ARE RARE IN COMPARATIVE DATA - Harmon - 2010 - Evolution - Wiley Online Library
05:49 < kanzure> .title http://onlinelibrary.wiley.com/doi/10.1111/j.1558-5646.2010.00959.x/abstract
05:49 < yoleaux> NOVEL COOPERATION EXPERIMENTALLY EVOLVED BETWEEN SPECIES - Harcombe - 2010 - Evolution - Wiley Online Library
05:50 < kanzure> .title http://onlinelibrary.wiley.com/doi/10.1111/j.1558-5646.2011.01444.x/abstract
05:50 < yoleaux> DIRECTIONAL SELECTION IN TEMPORALLY REPLICATED STUDIES IS REMARKABLY CONSISTENT - Morrissey - 2011 - Evolution - Wiley Online Library
05:53 < kanzure> .title http://www.nature.com/nature/journal/v467/n7313/abs/nature09342.html
05:53 < yoleaux> Epigenetic memory in induced pluripotent stem cells : Nature : Nature Publishing Group
05:53 < kanzure> "Here we observe that low-passage induced pluripotent stem cells (iPSCs) derived by factor-based reprogramming of adult murine tissues harbour residual DNA methylation signatures characteristic of their somatic tissue of origin, which favours their differentiation along lineages related to the donor cell, while restricting alternative cell fates. Such an ‘epigenetic memory’ of the donor tissue could be reset by differentiation and ...
05:54 < kanzure> ... serial reprogramming, or by treatment of iPSCs with chromatin-modifying drugs. In contrast, the differentiation and methylation of nuclear-transfer-derived pluripotent stem cells were more similar to classical embryonic stem cells than were iPSCs. Our data indicate that nuclear transfer is more effective at establishing the ground state of pluripotency than factor-based reprogramming, which can leave an epigenetic memory of the ...
05:54 < kanzure> ... tissue of origin that may influence efforts at directed differentiation for applications in disease modelling or treatment."
05:54 -!- Beatzebub_ [~beatzebub@d172-218-176-59.bchsia.telus.net] has quit [Quit: Beatzebub_]
06:11 < kanzure> .title http://www.nature.com/nrmicro/journal/v12/n6/abs/nrmicro3262.html
06:11 < yoleaux> The microbial ecology of permafrost : Nature Reviews Microbiology : Nature Publishing Group
06:13 < kanzure> .title http://www.nature.com/nrmicro/journal/v11/n2/abs/nrmicro2939.html
06:13 < yoleaux> Microbial life under extreme energy limitation : Abstract : Nature Reviews Microbiology
06:14 < kanzure> "A great number of the bacteria and archaea on Earth are found in subsurface environments in a physiological state that is poorly represented or explained by laboratory cultures. Microbial cells in these very stable and oligotrophic settings catabolize 10^4 to 10^6 -fold more slowly than model organisms in nutrient-rich cultures, turn over biomass on timescales of centuries to millennia rather than hours to days, and subsist with energy ...
06:14 < kanzure> ... fluxes that are 1,000-fold lower than the typical culture-based estimates of maintenance requirements. To reconcile this disparate state of being with our knowledge of microbial physiology will require a revised understanding of microbial energy requirements, including identifying the factors that comprise true basal maintenance and the adaptations that might serve to minimize these factors."
06:14 < kanzure> cool
06:24 < kanzure> "Other advances in sample collection have occurred outside of the conventional scientific ocean drilling programs that provide new opportunities for collecting deep biosphere samples. For example, revised giant piston coring devices for retrieval of longer (10 s of meters) sediment cores have been developed in both the USA (Røy et al., 2012) and France (Bourillet et al., 2007)."
06:31 -!- justanotherusr [~Justan@unaffiliated/justanotheruser] has quit [Read error: Connection reset by peer]
06:32 -!- justanotherusr [~Justan@unaffiliated/justanotheruser] has joined ##hplusroadmap
06:34 < ebowden> http://icb.oxfordjournals.org/content/42/2/369.full
06:35 < archels> .title
06:35 < yoleaux> Partner Choice in Nitrogen-Fixation Mutualisms of Legumes and Rhizobia
06:45 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 256 seconds]
06:45 < ebowden> http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093670
06:50 < ebowden> .title
06:50 < yoleaux> PLOS ONE: Evolutionary Dynamics of Nitrogen Fixation in the Legume–Rhizobia Symbiosis
06:53 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap
06:57 -!- TheBlight [~TheBlight@gatekeeper.bbp.ch] has quit [Quit: Textual IRC Client: www.textualapp.com]
08:01 -!- Porb [~Porbus@c110-22-139-137.mckinn4.vic.optusnet.com.au] has quit [Quit: Leaving]
08:04 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has quit [Ping timeout: 252 seconds]
08:06 -!- Porb [~Porbus@c110-22-139-137.mckinn4.vic.optusnet.com.au] has joined ##hplusroadmap
08:06 -!- Porb [~Porbus@c110-22-139-137.mckinn4.vic.optusnet.com.au] has quit [Client Quit]
08:13 -!- Porb [~Porbus@c110-22-139-137.mckinn4.vic.optusnet.com.au] has joined ##hplusroadmap
08:15 -!- ebowden_ [~ebowden@101.177.247.250] has joined ##hplusroadmap
08:15 -!- ebowden [~ebowden@101.177.247.250] has quit [Read error: Connection reset by peer]
08:17 -!- ebowden [~ebowden@2001:8003:1011:3f01:543f:6b50:da36:2e4] has joined ##hplusroadmap
08:17 -!- ebowden_ [~ebowden@101.177.247.250] has quit [Read error: Connection reset by peer]
08:24 -!- Taek [~quassel@2001:41d0:1:472e::] has quit [Quit: No Ping reply in 180 seconds.]
08:25 -!- Taek [~quassel@2001:41d0:1:472e::] has joined ##hplusroadmap
08:30 -!- Taek [~quassel@2001:41d0:1:472e::] has quit [Quit: No Ping reply in 180 seconds.]
08:30 -!- Taek [~quassel@2001:41d0:1:472e::] has joined ##hplusroadmap
08:38 -!- ebowden [~ebowden@2001:8003:1011:3f01:543f:6b50:da36:2e4] has quit [Remote host closed the connection]
08:53 -!- Stskeeps [~cvm@unaffiliated/stskeeps] has joined ##hplusroadmap
09:03 < kanzure> hm
09:06 -!- ebowden [~ebowden@2001:8003:1011:3f01:6521:fe4e:5538:3318] has joined ##hplusroadmap
09:12 -!- Porb [~Porbus@c110-22-139-137.mckinn4.vic.optusnet.com.au] has quit [Quit: Leaving]
09:17 -!- ThomasEgi [~thomas@2a02:810b:33f:dc18:f401:9fe5:ee84:a82b] has joined ##hplusroadmap
09:17 -!- ThomasEgi [~thomas@2a02:810b:33f:dc18:f401:9fe5:ee84:a82b] has quit [Changing host]
09:17 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has joined ##hplusroadmap
10:01 -!- ebowden [~ebowden@2001:8003:1011:3f01:6521:fe4e:5538:3318] has quit [Remote host closed the connection]
10:15 -!- xrr [~xrr@gprs-inet-183-94.elisa.ee] has quit [Ping timeout: 250 seconds]
10:30 -!- punsieve [~drandomtu@cpe-66-68-66-8.austin.res.rr.com] has joined ##hplusroadmap
10:44 -!- punsieve [~drandomtu@cpe-66-68-66-8.austin.res.rr.com] has quit [Ping timeout: 265 seconds]
11:04 -!- ant4t [~s3an@50.141.76.161] has joined ##hplusroadmap
11:08 -!- zadock [~outsider@81.180.210.87] has joined ##hplusroadmap
12:15 -!- ant4t [~s3an@50.141.76.161] has quit [Ping timeout: 246 seconds]
12:15 < kanzure> you guys are boring
12:29 -!- xrr [~xrr@gprs-inet-183-94.elisa.ee] has joined ##hplusroadmap
12:31 -!- Acty [uid89656@gateway/web/irccloud.com/x-mgwyqalbzgyikndn] has quit [Quit: Connection closed for inactivity]
12:38 -!- sheena [~home@S0106c8be196316d1.ok.shawcable.net] has joined ##hplusroadmap
12:42 -!- _0bitcount [~Big_Byte@81.61.208.88.dyn.user.ono.com] has joined ##hplusroadmap
12:49 -!- Viper168_ [~Viper@unaffiliated/viper168] has joined ##hplusroadmap
12:50 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 246 seconds]
12:52 -!- zadock [~outsider@81.180.210.87] has quit [Quit: Leaving]
12:54 -!- zadock [~outsider@81.180.210.87] has joined ##hplusroadmap
13:20 -!- Viper168_ is now known as Viper168
13:31 -!- Acty [uid89656@gateway/web/irccloud.com/x-xlizximcnklrudhi] has joined ##hplusroadmap
13:42 -!- xrr [~xrr@gprs-inet-183-94.elisa.ee] has quit [Ping timeout: 250 seconds]
13:46 < andytoshi> i met a biotech guy at a bar the other night and tried to get him to come here, but i doubt he knows how to use IRC
13:46 < andytoshi> also told him to look you up
13:57 -!- zadock [~outsider@81.180.210.87] has quit [Quit: Leaving]
13:59 -!- eudoxia_ [~eudoxia@r167-57-119-133.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap
14:00 -!- eudoxia_ [~eudoxia@r167-57-119-133.dialup.adsl.anteldata.net.uy] has quit [Client Quit]
14:02 < chris_99> http://digitalnature.slis.tsukuba.ac.jp/2015/06/fairy-lights-in-femtoseconds/
14:03 -!- eudoxia [~eudoxia@r167-57-127-242.dialup.adsl.anteldata.net.uy] has quit [Ping timeout: 276 seconds]
14:04 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Quit: Leaving]
14:04 -!- justanotherusr [~Justan@unaffiliated/justanotheruser] has quit [Ping timeout: 272 seconds]
14:16 -!- drewbot [~cinch@ec2-54-234-128-50.compute-1.amazonaws.com] has quit [Remote host closed the connection]
14:16 -!- drewbot [~cinch@ec2-54-82-84-3.compute-1.amazonaws.com] has joined ##hplusroadmap
14:24 -!- frant [~trygar@c-2ec305b4-74736162.cust.telenor.se] has joined ##hplusroadmap
14:24 < frant> hplus=transhumanism(human plus)
14:24 < frant> ?
14:24 < frant> what kind of hw/sw do you guys need?
14:25 -!- justanotherusr [~Justan@unaffiliated/justanotheruser] has joined ##hplusroadmap
14:43 -!- _0bitcount [~Big_Byte@81.61.208.88.dyn.user.ono.com] has quit [Quit: Leaving]
14:52 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-wifykiautezlnszg] has joined ##hplusroadmap
14:53 < kanzure> frant: we need giant death rays and kilometer-wide sattelite clouds
14:58 < chris_99> haha
14:58 < chris_99> how hard would it be, to make coloured rain i wonder
15:01 < kanzure> frant: also we need dna synthesis equipment
15:06 < frant> im talking about lowhanging fruit
15:06 < frant> cheap
15:06 < frant> to help accelerate the process
15:06 < frant> make things cheaper for you guys
15:06 < frant> ill be back tomorrow
15:06 -!- frant [~trygar@c-2ec305b4-74736162.cust.telenor.se] has quit [Quit: Leaving]
15:13 -!- Madplatypus [uid19957@gateway/web/irccloud.com/x-emjogppddcgnwxuj] has joined ##hplusroadmap
15:38 -!- strangewarp [~strangewa@c-76-25-206-3.hsd1.co.comcast.net] has quit [Ping timeout: 265 seconds]
16:19 -!- wrldpc1_ [~ben@228.22.150.119.ap.yournet.ne.jp] has joined ##hplusroadmap
16:20 -!- strangewarp [~strangewa@c-76-25-206-3.hsd1.co.comcast.net] has joined ##hplusroadmap
16:20 -!- wrldpc1 [~ben@133.131.169.216.client.dyn.strong-sf94.as22781.net] has quit [Ping timeout: 265 seconds]
16:20 -!- wrldpc1_ is now known as wrldpc1
16:32 < kanzure> https://medium.com/starts-with-a-bang/ask-ethan-94-could-dark-matter-not-exist-de5cd810e446
16:43 -!- punsieve [~drandomtu@cpe-66-68-66-8.austin.res.rr.com] has joined ##hplusroadmap
16:55 -!- nmz787_i [~ntmccork@134.134.139.72] has joined ##hplusroadmap
16:56 < nmz787_i> kanzure: those coasters could only be cooler if it was real brains
16:57 < kanzure> we could probably do that
16:57 < kanzure> slice a brain, then fixate it, then laminate it or put it between two pieces of plastic
16:59 < nmz787_i> those microtome imaging startups could probably actually /make/ some $$$ with coasters like that versus real science
17:05 < kanzure> yeah might be an interesting way to fund their work... but can't put that up on crowdstarter because it's animal matter.
17:06 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Remote host closed the connection]
17:12 -!- AmbulatoryCortex [~Ambulator@173-31-9-188.client.mchsi.com] has joined ##hplusroadmap
17:18 < nmz787_i> kanzure: what dates are the recent DNA talks in? (dang I still didn't come up with a web-based grepper that isn't google)
17:21 < nmz787_i> this shows 6 hits 'site:gnusha.org/logs/ 2015-06 dna'
17:21 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap
17:32 -!- delinquentme [~delinquen@74.61.157.78] has joined ##hplusroadmap
17:33 < kanzure> http://gnusha.org/logs/2015-06-19.log
17:33 < kanzure> http://gnusha.org/logs/2015-06-20.log
17:51 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-hyrcjnytmveiymbr] has joined ##hplusroadmap
17:57 < nmz787_i> fenn: CaptHindsight immune cells modify their own DNA... look up VDJ recombination
17:57 < nmz787_i> .wik VDJ recombination
17:57 < yoleaux> "V(D)J recombination, less commonly known as somatic recombination, is the unique mechanism of genetic recombination that occurs only in developing lymphocytes during the early stages of T and B cell maturation." — https://en.wikipedia.org/wiki/VDJ_recombination
18:15 < fenn> it's a very limited process
18:17 -!- nmz787_i [~ntmccork@134.134.139.72] has quit [Read error: Connection reset by peer]
18:20 -!- punsieve [~drandomtu@cpe-66-68-66-8.austin.res.rr.com] has quit [Ping timeout: 244 seconds]
18:50 -!- delinquentme [~delinquen@74.61.157.78] has quit [Ping timeout: 265 seconds]
19:00 -!- delinquentme [~delinquen@74.61.157.78] has joined ##hplusroadmap
19:02 < kanzure> hmm
19:20 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-wifykiautezlnszg] has quit [Quit: Connection closed for inactivity]
19:27 < CaptHindsight> nmz787: I was wondering how machinery can be supplied by nature vs me
19:37 < kanzure> we should really get back to project "rob all the graves of all the dead smart people to extract their skeletal dna remains"
19:37 < kanzure> e.g. some roadtrip
19:46 -!- rkos [~rkos@228.ip-176-31-189.eu] has quit [Remote host closed the connection]
20:22 < kanzure> .title https://news.ycombinator.com/item?id=9798374
20:22 < yoleaux> Could dark matter not exist? | Hacker News
20:32 -!- ebowden [~ebowden@2001:8003:1011:3f01:50f7:988f:27ca:ea0b] has joined ##hplusroadmap
20:35 -!- AmbulatoryCortex [~Ambulator@173-31-9-188.client.mchsi.com] has quit [Read error: Connection reset by peer]
20:47 -!- erasmus [~esb@unaffiliated/erasmus] has joined ##hplusroadmap
21:11 -!- Acty [uid89656@gateway/web/irccloud.com/x-xlizximcnklrudhi] has quit [Quit: Connection closed for inactivity]
21:43 -!- Porb [~Porbus@c110-22-139-137.mckinn4.vic.optusnet.com.au] has joined ##hplusroadmap
21:43 -!- Beatzebub [~beatzebub@d172-218-176-59.bchsia.telus.net] has joined ##hplusroadmap
21:44 -!- Porb [~Porbus@c110-22-139-137.mckinn4.vic.optusnet.com.au] has quit [Client Quit]
22:07 -!- erasmus [~esb@unaffiliated/erasmus] has quit [Quit: Namaste	]
22:23 -!- delinquentme [~delinquen@74.61.157.78] has quit [Ping timeout: 255 seconds]
22:24 -!- xrr [~xrr@gprs-inet-183-94.elisa.ee] has joined ##hplusroadmap
22:38 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-hyrcjnytmveiymbr] has quit [Quit: Connection closed for inactivity]
22:43 -!- Porb [~Porbus@c110-22-139-137.mckinn4.vic.optusnet.com.au] has joined ##hplusroadmap
23:06 -!- Acty [uid89656@gateway/web/irccloud.com/x-ehpffhjdbmykqccb] has joined ##hplusroadmap
23:08 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Quit: Leaving]
23:12 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap
23:16 -!- knobuddy [~Xial@unaffiliated/knobuddy] has joined ##hplusroadmap
23:19 -!- delinquentme [~delinquen@74.61.157.78] has joined ##hplusroadmap
23:24 -!- delinquentme [~delinquen@74.61.157.78] has quit [Ping timeout: 252 seconds]
23:38 -!- xrr_ [~quassel@gprs-inet-183-94.elisa.ee] has joined ##hplusroadmap
23:51 -!- xrr_ [~quassel@gprs-inet-183-94.elisa.ee] has quit [Remote host closed the connection]
23:54 -!- berndj [~berndj@azna.co.za] has quit [Quit: ZNC - http://znc.in]
23:54 -!- berndj [~berndj@azna.co.za] has joined ##hplusroadmap
--- Log closed Tue Jun 30 00:00:56 2015