--- Log opened Mon Oct 24 00:00:30 2016
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02:02 < archels_> .title http://www.eha-heales.org/declaration.html
02:02 < yoleaux> Declaration - 2016 Eurosymposium on Healthy Ageing
02:02 < archels_> The Brussels Declaration for Radical Healthspan Extension
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03:19 < fenn> step 1) don't die. step 2) ??? step 3) profit!  which presumably includes being healthy
03:20 < fenn> in summary, not dying is a pre-requisite to being healthy
03:21 < fenn> not the other way around, as this website seems to claim
03:22 < fenn> sure being healthy also keeps you from dying
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05:56 < JayDugger> A bit of an overstatement there, fenn. Good health provides very little defense against fatal accidents: automobile crashes, drowning, earthquake, etc.
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06:01 < Urchin> a well built house/building does protect against earthquakes, though, it also helps with health
06:02 < archels_> good health doesn't do anything against programmed death either
06:02 < archels_> I think that's the main drive of the argument here, against the rectangularization of the age distributioni
06:03 < Urchin> archels_: not quiet, programmed death has a sudden onset, often due to an event that causes diminished health
06:04 < Urchin> it's still usually an accident that triggers terminal aging
06:14 < archels_> what? aging is the most common cause of death by an overwhelming factor
06:18 < Urchin> yes, it is
06:19 < Urchin> but terminal aging is a fairly short process of several months, and is usually triggered by some accident lowering general health
06:21 < Urchin> it functions like a cascading failure
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08:39 < kanzure> ".. behavioral results indicate that even high-functioning individuals with ASD perform less accurately and more slowly than neurotypical (NT) controls when processing eyes, but not when processing a directional cue (an arrow) that did not involve eyes" http://online.liebertpub.com/doi/abs/10.1089/brain.2013.0161
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09:23 < kuudes> ah, yeah. people here could be interested of http://mielik.fi
09:23 < kuudes> it is a retakeable iq test I have made - a use case for such is to measure one's iq before and after intervention to get evidence on intervention's effectiveness
09:25 < kuudes> currently, the iq normalization of it is still ongoing, as it has not met very many people, but the internal score it returns should be much more constant, ie that you could compare your score on time 1 to your score on time 2; and you could try to deduce correlations etc from those score
09:25 < kuudes> if you want to try it, feel free. it is currently in open beta. I have made the testlets, the machine learning algorithm and the software system.
09:26 < kuudes> if you want further information or to talk on the subject, please feel free to join #mielik
09:30 < pasky> now I remember why I hate IQ tests, thanks! :)
09:33 < kanzure> because of the tendency of people to draw strenuous conclusions from the concept of iq and iq test results?
09:33 < kuudes> there are many valid criticisms against iq tests; and a major drawback so far has been that they are not repeatable, so one can't really use them as a meter for self improvements and quantified self; this system aims to cross that gap, so my sincere hope is that it would be useful for quantified self practicers
09:36 < pasky> I think I got bored, sorry; from the first 9 questions, I could answer three (not sure if correctly); took one other IQ test in my life, a random high school thing with score I think around 135, not sure anymore
09:36 < pasky> hth
09:36 < kanzure> i think there was a study somewhere about personal beliefs about intelligence as influencing intelligence test results or something. some sort of correlation to arrogance and conscientiousness. not sure where this study went though. so i'm talking out of my butt flaps.
09:38 < kuudes> yeah, it has hopefully a higher range for where it gives measurements; this means that some testlets will feel impossibly hard and some testlets boringly easy for some people. human cognitive range is large
09:38 < pasky> I suggest starting with the easier ones then :)
09:38 < kuudes> there are functional obstacles on doing that, I am afraid
09:38 < pasky> also the page was really slow to load sometimes (like ~5 seconds), not sure how much weight do you give to time taken
09:39 < kuudes> hmm. I wonder why it would be slow, I'll check. thanks for that info, it should not be
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09:39 < pasky> kuudes: then i think your test is impractical
09:39 < pasky> because people need warmup and sustaining motivation to go through it
09:40 < kuudes> what sort of browser/isp configuration you have, it does not seem to behave slowly for my test run?
09:41 < pasky> chrome / upc.cz
09:42 < kuudes> hmm. I wonder if it would be related to the current/recent iot attack thing, not sure
09:42 < kuudes> it should not have but a simple handwritten javascript and svgs on client side
09:43 < kuudes> I guess I should test it through some foreign anonymizer to see if hosting isp has problems to abroad; I would presume it should not have, but one never knows
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09:44 < pasky> actually I'm not 100% sure now it's not a connectivity problem on my side that started during the test, sorry!
09:46 < kuudes> it does not seem to show through kproxy at least
09:47 < kuudes> in any case, thank you for this information
09:48 < kuudes> I don't think I have much more to trouble the channel with, if it is useful for you, use it, etc. if you need something from me, I am at #mielik
09:48 < kuudes> thanks
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09:54 < kanzure> ah the relevant query is "beliefs about intelligence" apparently
09:58 < maaku> I was musing this morning that there should be an open source seed project, and indeed there is: http://osseeds.org/
09:59 < maaku> But it doesn't look like they're doing any genetic engineering.
09:59 < maaku> There should be someone cleanroom engineering superior seeds to Monsanto et al
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10:01 < pasky> maaku & kanzure: are you still working on the speech reco project? any interesting news? :)
10:03 < maaku> yes still working on it, not sure there's anything 'interesting' to report
10:07 < kanzure> just plodding along, setting up various infrastructure pieces.
10:08 < kanzure> i expect a long grueling period of tweaking models and waiting for test results.
10:13 < kanzure> also trying to figure out how much custom code can be dumped into google cloud ml https://cloud.google.com/ml/docs/how-tos/preparing-models
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10:29 < fenn> the countdown timer on the IQ test attracts all of my attention
10:29 < fenn> no thanks
10:29 < fenn> too stressful
10:30 < chris_99> are iq tests normally timed?
10:31 < fenn> i don't know
10:31 < maaku> I wonder how much it would cost to cleanroom genetically engineer one suprior crop, something big like rice or corn
10:31 < maaku> That's probably something you could get a philantropy group to fund.
10:32 < maaku> Most of your costs would be patent lawyers though...
10:39 < kanzure> it woud be cheaper to do random mutagenesis and then harvest and then check for interesting strains
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10:40 < kanzure> i don't think we presently have easy ways to control leaf surface area or root cross-section diameter vs length stuff.
10:40 < fenn> i disagree. we know a lot about why crops fail and what could be changed to make them better
10:40 < fenn> random mutations are not going to give you sudden functional improvements
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10:42 < kanzure> bruteforce sucks but it works.
10:43 < maaku> it is far too slow
10:44 < maaku> you're not going to catch up to, let alone surpass the intelligently designed seeds of Monsanto
10:44 < kanzure> they have like only one or two tweaks, who cares
10:44 < fenn> also for OSSI in particular, we have genomes from burbank potatoes and whatever patented crops people already like but can't use due to legal reasons, but probably only a couple genes are responsible for why they are the preferred strain vs other unpatented ones, and you can just copy that specific gene into your "open source" potato
10:44 < maaku> whaaa? I think that is a gross mischaracterization of the state of the industry
10:45 < fenn> because plant patents mostly happened way before genetic engineering
10:45 < maaku> GMOs have a lot more than "one or two tweaks" they are radically different
10:46 < fenn> i expect the people behind OSSI are radicalyl anti-GMO anyway
10:47 < fenn> because friggin everyone is
10:47 < pasky> maaku & kanzure: thanks for the update - wish you luck! will ping again in a month or so :) we were thinking about making a business experiment with voice-related stuff at ailao but we got discouraged with the lack of good datasets and having to deal with b2b marketing
10:47 < maaku> probably. i don't really care about GMO vs non-GMO.. i'm more anti-rent-seeking
10:47 < maaku> in my motivation
10:47 < maaku> Monsanto must die.
10:47 < fenn> "OSSI does not currently accept material containing transgenic (GMO) components for designation as an OSSI variety. Given the on-going societal conversation around both demonstrable and possible ecological effects, the close ties between GMO’s development and restrictive intellectual property arrangements, and the discomfort expressed within the OSSI community regarding transgenic plants, we do
10:47 < fenn> not feel that GMO material is currently appropriate for OSSI."
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10:48 < fenn> "the close ties between GMO’s development and restrictive intellectual property" is a particulary stupid argument for this particular project
10:49 < maaku> exactly...
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10:54 < fenn> i wonder if there are any legal loopholes around the phrase "of extraterrestrial origin" that can be gamed by producing things on mars
10:55 < fenn> like an insurance fraud service that bombs your house with meteors
10:55 < fenn> or circumventing plant patents
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10:58 < maaku> i've always wanted to legally change my name to "God", so I could be responsible for Acts of God
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11:10 < kanzure> somehow i would think there would be more expedient ways to commit insurance fraud
11:11 < fenn> no no i'm looking for excuses to go to mars
11:11 < kanzure> they need more?
11:13 < kanzure> got any evidence about "more than a few tweaks"
11:13 < kanzure> ?
11:18 < fenn> i thought it was just glyphosate resistance but my info is probably a couple decades out of date
11:19 < kanzure> are the roof gremlins still torturing you?
11:20 < fenn> no they finished yesterday
11:24 < fenn> why isn't it more common for elderly people to take neural growth factors? it seems worth it just for the novelty boost
11:24 < fenn> lion's mane for example
11:25 < fenn> there are a lot of people who just give up at life because all their friends have died of old age
11:25 < fenn> and that's a stupid reason to die
11:26 < kanzure> yes well, give them something to do instead, like endless oral history interrogation sessions or something
11:27 < kanzure> "exit interview"
11:27 < fenn> they're just humoring the youngsters at that point
11:27 < fenn> not really wanting to live
11:28 < fenn> hmm... " Acetyl L Carnitine, which multiplies the effect of NGF by 100"
11:28 < kanzure> motivation drug could work; although i think old folks probably get lost re: social roles and what to do with an abundance of time.
11:28 < fenn> yes and what i'm saying is they have stopped learning
11:29 < fenn> because they ran out of empty synapses
11:29 < fenn> so make some new synapses
11:30 < fenn> combined with a healthy dose of externally inflicted doubt in one's self image, they are almost guaranteed to become interested in something new and different
11:31 < kanzure> synapse depletion doesn't sound like a good reason to me; if anything, you would see lots of old people very actively engaging in things, and then forgetting everything regularly, but still continuing to make attempts. instead you see isolation and low energy low cognitive engagement.
11:31 < fenn> a large part of the challenge is getting people to believe they are actually still useful
11:32  * fenn ignores the impending robocalypse for the moment
11:33 < kanzure> in fact for synapse depletion to be the right answer then you would have to also claim that most daily human cognitive "executive function" is a property of having an abundance of available synapse for daily cognitive load stuff.
11:33 < kanzure> (which isn't any more strange or weird; in fact that part is probably less weird than the first claim you made.)
11:34 < fenn> when i took lion's mane i started getting interested in all sorts of things which were totally at odds with my self image
11:35 < kanzure> is there anything that blocks out infinite amounts of noise
11:35 < fenn> i dunno, piracetam helps with signal to noise ratio
11:35 < fenn> endogenous noise at least
11:36 < kanzure> i mean the concentration thing where you have to push everything out
11:36 < fenn> people claim modafinil helps with focus
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11:43 < nmz787_i> http://www.cs.ubc.ca/labs/isd/Projects/monosat/
11:44 < nmz787_i> started working on a 3D autorouter for microfluidics using that.... worked with a simplistic encoding, but that won't scale, so working on using the graph awareness to my advantage
11:45 < kanzure> for routing just use vlsi routers
11:45 < nmz787_i> not as amenable to code changes I suppose
11:46 < nmz787_i> from what I remember, the best open router was freerouting, which was massively more complex than the program I've got so far (~300 lines)
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14:05 -!- Topic for ##hplusroadmap: biohacking, nootropics, transhumanism, open hardware | sponsored by lobsters everywhere, banned by the Federal Death Administration (5 times) | this channel is LOGGED: http://gnusha.org/logs | http://diyhpl.us/wiki | "ray kurzweil is a pessimist" - george church
14:05 -!- Topic set by kanzure [~kanzure@unaffiliated/kanzure] [Wed May 20 12:46:25 2015]
14:05 [Users ##hplusroadmap]
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14:05 -!- Channel ##hplusroadmap created Thu Feb 25 23:40:30 2010
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15:30 < superkuh> c2 wiki has fallen to modern web design sickness after the recent server problems. It has now removed all text and replaced it with javascript.
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16:24 < nsh> uugh
16:28 < kanzure> yea
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18:11 < kanzure> https://github.com/maxhodak/keras-molecules "We report a method to convert discrete representations of molecules to and from a multidimensional continuous representation. This generative model allows efficient search and optimization through open-ended spaces of chemical compounds."
18:11 < kanzure> yeah but if we had access to the organic transformation mechanism databases then we wouldn't need to do bruteforce stuff >:(
18:11 < kanzure> er i mean, bruteforce "learning"
18:26 < kanzure> https://hpluspedia.org/index.php?title=Special:RecentChanges&limit=500
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19:06 < kanzure> .wik esiniferatoxin
19:06 < kanzure> er..
19:06 < yoleaux> kanzure: Sorry, I couldn't find article.
19:06 < kanzure> .wik resiniferatoxin
19:06 < yoleaux> "Resiniferatoxin (RTX) is a naturally occurring chemical found in resin spurge (Euphorbia resinifera), a cactus-like plant commonly found in Morocco, and in Euphorbia poissonii found in northern Nigeria. It is an ultrapotent analog of capsaicin, the active ingredient in chili peppers." — https://en.wikipedia.org/wiki/Resiniferatoxin
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