--- Log opened Mon Mar 31 00:00:02 2025 02:35 -!- TMM [hp@amanda.tmm.cx] has quit [Quit: https://quassel-irc.org - Chat comfortably. Anywhere.] 02:35 -!- TMM [hp@amanda.tmm.cx] has joined #hplusroadmap 02:38 -!- darsie [~darsie@84-113-82-174.cable.dynamic.surfer.at] has joined #hplusroadmap 02:43 -!- gl00ten [~gl00ten@194.117.18.100] has joined #hplusroadmap 02:43 -!- gl00ten [~gl00ten@194.117.18.100] has quit [Remote host closed the connection] 02:44 -!- gl00ten [~gl00ten@194.117.18.100] has joined #hplusroadmap 02:50 -!- gl00ten [~gl00ten@194.117.18.100] has quit [Ping timeout: 252 seconds] 04:41 -!- srk [~sorki@user/srk] has quit [Ping timeout: 248 seconds] 05:35 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has quit [Ping timeout: 244 seconds] 06:33 -!- srk [~sorki@user/srk] has joined #hplusroadmap 08:15 -!- justanotheruser [~justanoth@gateway/tor-sasl/justanotheruser] has quit [Ping timeout: 264 seconds] 08:24 -!- darsie [~darsie@84-113-82-174.cable.dynamic.surfer.at] has quit [Quit: Avoid fossil fuels and animal products. Have no/fewer children. Protest, elect sane politicians. Invest ecologically.] 08:25 -!- darsie [~darsie@84-113-82-174.cable.dynamic.surfer.at] has joined #hplusroadmap 08:27 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has joined #hplusroadmap 09:00 < kanzure> is there a window manager that treats the desktop as an ~infinite 2d canvas and encourages applications to not manage scrollboxes themselves? for example, a 500 page book with all 500 pages on the full canvas (user's displayer would only render one page at a time) 09:01 < kanzure> browser tabs should not be tabs, but separate windows; and the browser should not manage the viewport or scroll index. if it's a "long" webpage, it should take up more space on the canvas than a "short" webpage 09:01 < kanzure> also, i should be able to create new bookmarks or views on any displays, tabs, views, windows and add them into my alt-tab stack 09:03 < kanzure> i wouldn't want all of that to actually render all the time, of course, it's more about the underlying data model and user interface 09:12 < ike8> that seems like it would be much more resource intensive 09:41 < kanzure> just don't actually render it 11:04 -!- justanotheruser [~justanoth@gateway/tor-sasl/justanotheruser] has joined #hplusroadmap 11:13 < L29Ah> https://www.lifespan.io/news/joshua-scotch-mcclure-infectious-disease-drives-aging/ 12:39 -!- superkuh [~superkuh@user/superkuh] has quit [Read error: Connection reset by peer] 12:39 -!- superkuh [~superkuh@user/superkuh] has joined #hplusroadmap 12:45 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has quit [Ping timeout: 252 seconds] 12:45 < hprmbridge> kanzure> https://github.com/backnotprop/prompt-tower 12:52 < RangerMauve> kanzure: I kinda do something like that with my web browser agregore.mauve.moe combined with this Linux "infinite scroll" window manager called niri https://github.com/YaLTeR/niri 13:12 < kanzure> "and there's always one empty workspace present all the way down." what does this mean? 13:37 -!- saxo [~saxo@zug.infomesh.net] has quit [Remote host closed the connection] 13:37 -!- saxo [~saxo@zug.infomesh.net] has joined #hplusroadmap 14:38 < RangerMauve> kanzure: Some linux distros have a finite set of workspaces configured, niri creates as many as you want on the fly I guess. I just use the horizontal scroll and ignore the workspaces tbh 14:55 < kanzure> oh 15:01 < kanzure> RangerMauve: see DM 15:02 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has joined #hplusroadmap 15:55 < fenn> wow that synthetic LL-37 article is unbelievable 15:57 < fenn> maxwell biosciences "claromers" are defensin peptides but the side chains shifted over to the nitrogen of the amino acid 15:58 < fenn> they claim it kills gram positive, gram negative, fungi, viruses 16:00 < fenn> no toxicity detectable, shelf stable, heat resistant, based on an extremely well studied natural peptide produced by the human body 16:01 < fenn> aka 16:01 < fenn> Cathelicidin antimicrobial peptide 16:04 -!- andytoshi [~apoelstra@user/andytoshi] has quit [Ping timeout: 248 seconds] 16:14 -!- TMM [hp@amanda.tmm.cx] has quit [Quit: https://quassel-irc.org - Chat comfortably. Anywhere.] 16:14 -!- TMM [hp@amanda.tmm.cx] has joined #hplusroadmap 16:16 -!- andytoshi [~apoelstra@user/andytoshi] has joined #hplusroadmap 17:02 -!- Gooberpatrol66 [~Gooberpat@user/gooberpatrol66] has quit [Quit: Konversation terminated!] 17:03 -!- Gooberpatrol66 [~Gooberpat@user/gooberpatrol66] has joined #hplusroadmap 17:03 < hprmbridge> Eli> I think the question I would have is “why doesn’t the body up regulate ll37 already? The immune system is a balancing act. Is there autoimmune risk? Guess we will find out at some point. 17:11 -!- Gooberpatrol_66 [~Gooberpat@user/gooberpatrol66] has joined #hplusroadmap 17:11 -!- Gooberpatrol66 [~Gooberpat@user/gooberpatrol66] has quit [Ping timeout: 260 seconds] 17:32 < jrayhawk> https://scholar.google.com/scholar?q=ll-37+cancer it has its downsides 17:40 -!- drmeister [sid45147@id-45147.ilkley.irccloud.com] has quit [] 17:40 -!- drmeister [sid45147@id-45147.ilkley.irccloud.com] has joined #hplusroadmap 17:42 < jrayhawk> some of the tradeoffs the immune system are making are between things like bacterial/fungal/archael infection, multicellular parasite infection, viral infection, various kinds of toxin cleanup, and cancer. Additionally, as you imply, if you're releasing piles of cytokines constantly without anything valid to attack, the immune system will start attacking invalid things. 17:54 < hprmbridge> Eli> archael infection? 18:32 < jrayhawk> er, archaeal 18:32 < jrayhawk> awkward spelling 18:51 -!- darsie [~darsie@84-113-82-174.cable.dynamic.surfer.at] has quit [Ping timeout: 244 seconds] 19:04 -!- darsie [~darsie@84-113-82-174.cable.dynamic.surfer.at] has joined #hplusroadmap 19:43 -!- darsie [~darsie@84-113-82-174.cable.dynamic.surfer.at] has quit [Ping timeout: 244 seconds] 22:20 -!- gAy_Dragon is now known as AI_Dragon 23:21 -!- TMM [hp@amanda.tmm.cx] has quit [Quit: https://quassel-irc.org - Chat comfortably. Anywhere.] 23:21 -!- TMM [hp@amanda.tmm.cx] has joined #hplusroadmap --- Log closed Tue Apr 01 00:00:03 2025