# Key Points from #hplusroadmap IRC Discussion

• Participants explored non-invasive optogenetic technology possibilities, debating delivery methods like electroporation while raising concerns about safety and practicality for neural applications.

• Kanzure shared a DIY microfluidics technique using sharpie markers on glass slides, where the hydrophobic ink creates channels for directing water flow, potentially enabling "lab on a chip" applications including PCR and DNA sequencing.

• Several microfluidics research papers were discussed, with particular focus on DNA separation techniques using principles like asymmetric obstacles, hydrodynamic forces, gravity, dean vortices, and bifurcation.

• The group explored how microfluidic devices can perform gel-free electrophoresis using arrays of obstacles that affect DNA movement based on molecule size, with debate about whether DNA should remain bundled or straightened during this process.

• A paper on microthermal devices for fluidic actuation through surface tension modulation was highlighted as particularly important for DIY microfluidics applications.

• The concept of a "mobile fab lab" or "mobile fabratory" with laser printing technology was discussed, suggesting interest in democratizing fabrication technologies for wider accessibility.