# Key Points from #hplusroadmap IRC Discussion

• Researchers discussed a significant reproductive technology breakthrough involving female germline stem cells from adult mice that could generate offspring when transplanted into infertile animals.

• Detailed proposals for DIY DNA synthesis methods were shared, including a maskless lithography DNA synthesizer using LCD screens with photolabile protecting groups, with estimated chemical costs around $60.

• Several microfluidic technologies were discussed, including spiral microchannel PCR systems and laser-driven micropumps using ultrasonic cavitation for blood cell lysis.

• Participants explored OLED fabrication methods for potential use in DNA synthesis applications, noting concerns about indium availability and discussing alternative cathode fabrication techniques.

• The conversation highlighted tensions between DIYbio and academic synthetic biology communities, with observations that iGEM students typically have more practical molecular biology experience but DIYbio might develop novel techniques due to resource constraints.

• An open-source space exploration team competing in the Google Lunar X Prize sought collaborations on autonomous exploration technologies, prompting debate about the feasibility of private space ventures and open-source hardware development for space applications.

• Researchers shared advances in stem cell technology, particularly using microRNAs for reprogramming adult cells into embryonic stem cells, alongside ethical debates about genetic modification of embryos.