# Summary of #hplusroadmap IRC Log (May 29, 2009)

* Discussion of nucleoside mimics (ligandosides) with reference to Elsevier research, including a link to a paper on the topic.

* Conversation about DNA polymerase modification techniques, including blocking the template strand site with light-responsive molecules and using in vitro compartmentalization to improve artificial nucleotide incorporation.

* Reference to RNA engineered for counting in living cells, with debate about its potential for intra-cellular computing and the limitations of binary vs. ternary encoding systems in biological contexts.

* Technical discussion of spiral filter technology for algae harvesting, with participants sharing spectrophotometry data showing increased absorbance after multiple filtration cycles and discussing potential for selective breeding of easily harvestable algae.

* Comparison of manual vs. automated cell counting methods, with participants advocating for ImageJ software over traditional microscope counting techniques.

* Brief exchange about gray code vs. binary encoding for noise resistance in biological systems, with explanation of how gray code changes only one bit at a time to reduce error propagation.

* Speculative discussion about currency systems for space exploration, including radiation-resistant designs and self-contained transaction verification for off-planet economies.

* Mention of functional near infrared spectroscopy (fNIRS) technology for monitoring neural activity and brain states in pilots to detect dangerous levels of stress and fatigue.