# Key Points from IRC Log

• A discussion about creating a low-cost Scanning Electron Microscope (SEM) revealed that commercial options like "mySEM" start at around $100K, with participants expressing interest in finding or building more affordable alternatives in the $1-10K range.

• The group discussed DIY Atomic Force Microscope (AFM) projects, including one with CAD models for plastic components, parts lists, and assembly instructions, referenced in a paper titled "Print your AFM" or "How to build a Plastic-AFM head."

• Participants shared information about DIY biology projects, including NYC's DIY BIO group inserting Green Fluorescent Protein genes into DNA and Kay Aull's home DNA lab for genotyping her HFE gene.

• A detailed technical discussion about simplifying laboratory equipment occurred, with one participant suggesting that gel electrophoresis could be performed with household items and a hot glue gun rather than expensive lab equipment.

• The group discussed the POSaM project, an open-source inkjet oligonucleotide synthesizer and microarrayer, as documented in a shared PDF.

• Concerns were raised about copyright issues with hosting academic papers, leading to the creation of a notice to publishers on the group's file-sharing server stating papers were for academic purposes only.

• Members discussed chemistry synthesis challenges, including creating precursors for photolabile phosphoramidites without relying on commercial suppliers like Sigma Aldrich.