# Key Technical and Conceptual Discussions from #hplusroadmap

• The SKDB (Software Kit Database) project emerged as a central focus, aiming to create infrastructure "glue" that would package DIY instructions for both procedures and tools, with part mating algorithms identified as a near-term development milestone.

• Participants worked on integrating pythonOCC (a 3D modeling library) with pymates for mechanical design, sharing code and troubleshooting implementation challenges related to YAML custom tags, interface definitions, and object attributes.

• Researchers discussed advanced protein purification techniques using CD-based devices with MPTS-crosslinked columns, comparing their principles to gel electrophoresis and analyzing how fragment size affects travel speed.

• A significant materials science resource was shared—a 479MB MatWeb database containing information on approximately 80,000 materials—alongside efforts to develop a comprehensive material database with mechanical and optical properties.

• The group explored automated design compatibility methods that could identify chains of tools implementing the same solution despite different appearances, using clustering techniques and Design Structure Matrix adjacency matrices to compare design outcomes.

• Augmented reality applications were discussed, particularly face recognition capabilities using OpenCV that could identify and classify faces in real-time video streams with overlaid information, with criticism that current AR hardware manufacturers lack vision for complete solutions.

• H+ (formerly WTA) appears to be shifting focus from philosophical transhumanism toward practical infrastructure projects, including building a DIYbio lab and potentially funding independent research projects.