# Summary of #hplusroadmap IRC Discussion (Sept 18, 2009)

• Discussion of manufacturing automation and function structures, focusing on how to handle compatibility between parts with different ranges of acceptable values (e.g., pressure ranges in pipes) and the potential for "drift" in connected components.

• Exploration of cognitive enhancement drugs, with a user reporting on their experience with adrafinil (600mg) compared to modafinil, noting it "kicks in slowly" but wears off after about 8 hours, requiring higher dosages.

• Technical conversation about sentence planners and PDDL (Planning Domain Definition Language) problems, with references to PAR (Parameterized Action Representation) systems for natural language processing.

• Sharing of resources on meshing algorithms and mathematical distributions, including links to papers at www.ann.jussieu.fr/~frey/papers/meshing/ and R statistical package distributions.

• Discussion of DIY biology efforts, specifically regarding methods for purifying restriction enzymes using histidine tagging and the challenges of determining purity and enzyme activity units.

• Reference to a paper titled "A port ontology for conceptual design of systems" by Paredis, which appears to be significant for conceptual system design methodology.