# Key Points from #hplusroadmap IRC Discussion (Nov 29, 2009)

• SKDB (Standard Kit of Design Blocks) development focused on improving installation documentation for Ubuntu 9.10, including automated setup procedures for dependencies like PythonOCC, with consensus on using /usr/local/share/skdb/ as the standard filesystem location.

• Participants discussed creating a generalized dependency framework for knowledge representation that would formalize teaching order and prerequisite structures across different domains of knowledge.

• The group debated molecular manufacturing approaches, particularly expressing skepticism about Merkle and Freitas' "design ahead" strategy for diamondoid mechanosynthesis that assumes bootstrapping methods will be developed later.

• Technical limitations of AFM (Atomic Force Microscopy) tool tips were discussed, noting their short operational lifetime of approximately 1000 seconds even in vacuum conditions, which presents challenges for nanomanufacturing.

• Bioprinting techniques using hydrogel-based substrates (bio-paper) and cell suspensions (bio-ink) were explored, with specific references to formulations like soy agar gel and collagen gel, along with sharing of a hydrocolloid recipe collection relevant to bioprinting materials.

• Git repository management techniques were shared, including methods to extract subsets of files into separate repositories and optimize repository size, alongside development of a web interface with features for viewing commit logs and branch management.