# Key Points from #hplusroadmap IRC Discussion

• Participants discussed genome sequencing technologies, including solid-state nanopore systems that could potentially reduce sequencing costs to $100, with related conversations about AFM-DNA-sequencing papers and advancements in nanopore technology.

• Kanzure shared an open-source PCR machine project called Thermotyp by Otyp.es that aims to make thermal cyclers more affordable by leveraging open technologies and mass-produced computer parts, with design files available on Thingiverse.

• The group debated the need for a clear definition of "open source hardware" similar to established software guidelines, discussing challenges related to commercial distribution, modification rights, and how traditional software licenses like GPL don't adequately address hardware manufacturing issues.

• Collaborative mathematics and programming tools were explored, including Sage and SymPy, with suggestions for combining features from platforms like etherpad to create better collaborative environments for mathematicians.

• The Open Source Ecology (OSE) project was critiqued regarding their custom licensing approach and tool choices, with concerns about their use of OpenPario instead of standard revision control systems.

• A Food Commons Hydro project involving rainwater collection for hydroponics was mentioned, with interest in its potential compatibility with salt-water hydroponics systems.

• One participant proposed using k-means clustering and statistical analysis of "improbable phrases" as a method for automatically summarizing IRC conversations, addressing the need for automated topic summarization.