# Key Points from #hplusroadmap IRC Discussion

• Participants discussed biohacking applications, including Todd Huffman's magnetic finger implants that can detect electric fields through vibration, representing practical examples of body modification for enhanced sensory capabilities.

• The conversation compared influential transhumanist thinkers, with David Pearce's work being highlighted as more substantive than Nick Bostrom's, showing how the community evaluates theoretical contributions to the movement.

• Silicos NV was noted for transitioning their proprietary computational chemistry software to open source under GNU GPL, including tools for molecular design using evolutionary algorithms, demonstrating a shift toward open science in biotechnology.

• Development updates on SKDB (package management for physical objects) were shared, including the conversion of Thingiverse datasets to SKDB-like packages at designfiles.org, showing progress in standardizing digital fabrication resources.

• Technical discussions covered microfluidic computing challenges, particularly regarding memory implementation using fluidic flip-flops and oil droplets in low Reynolds number environments, illustrating exploration of alternative computing paradigms.

• Participants evaluated cognitive enhancement through modafinil, with specific dosage experiences shared (600mg causing side effects, 200-300mg suggested as more appropriate), reflecting the community's practical approach to nootropics and performance enhancement.

• The group expressed concerns about the progress of major AGI projects, noting that OpenCog appeared stalled due to personality conflicts while SIAI's Friendly AI work showed limited visible development despite extensive theoretical discussion.