# Key Points from #hplusroadmap IRC Discussion

• Jordan Miller shared his innovative tissue engineering work developing a scalable, inexpensive method for creating tissue mimics by printing scaffolds rather than directly printing cells, allowing dozens of ~1mL tissue samples to be produced daily.

• A research team is working on vascularized engineered liver constructs under a 5-year NIH grant, using nanoparticles for non-invasive monitoring of tissue vascularization, though progress is slowed by limited funding.

• Recordings from the French transhumanist association's first conference were shared by Utopiah and are available at http://vimeo.com/channels/164832, though without subtitles.

• Participants discussed prosthetics development, particularly the challenges of creating nerve-controlled mechanical arm replacements that don't require external power cords.

• Lukas shared research on how cancer cells evade immune detection by down-regulating MHC class 1 molecules, suggesting this mechanism could potentially be used to temporarily bypass immune responses when incorporating new DNA into organisms.

• A paper on intracranial hemodynamics was discussed, noting that craniotomy may increase cerebral blood flow by approximately 8-10%, which was humorously framed as a potential "upgrade."

• Aubrey de Grey, prominent longevity researcher, had recently joined Quora and was working on converting the H+ Magazine website from Drupal to WordPress.