# Key Points from IRC Discussions

• Researchers discussed next-generation DNA sequencing technologies, noting approximately 25 companies pursuing affordable genome sequencing ($1000-$100 genome), with single-molecule sequencing (3rd generation) being particularly promising for enabling DIY biology once costs decrease.

• A biohacker shared research on protein-based immune suppressants, specifically variants of MHC found in fetuses that prevent miscarriages, which could potentially address tissue rejection issues in transplantation and biohacking.

• The Gada Prize ($80k for open-source hardware) was discussed, with the R&D director planning to address concerns about teams keeping work secret by requiring open publication of schematics throughout the development process.

• Participants explored memristors and neuromorphic engineering, speculating how these technologies might revolutionize machine learning and programming, with HP developing memristor technology that could make them relevant in computing again.

• The group debated decentralized computing alternatives to centralized web services, discussing distributed systems like Kademlia DHT and Netsukuku as potential solutions for privacy and freedom from central control.

• Research on circadian rhythms in human red blood cells was shared, noting that peroxiredoxin proteins undergo ~24-hour redox cycles without external cues, suggesting possibilities for DIY experiments with blood cell cultures.

• The conversation touched on transhumanist philosophy, including debates about personal identity in scenarios like mind uploading, with one participant defining H+ as "the sentient use of technology to improve quality of life."