# Summary of IRC Log from #hplusroadmap (April 30, 2011)

* A user discussed plans for bacterial transformation with lactobacillus from yogurt as a stepping stone toward human genetic engineering, noting that "engineering gut flora is the way to go until I can get some more gene therapy experience."

* Kanzure shared a significant paper on stem cell research: "Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency," which claimed to be two orders of magnitude more efficient than standard Oct4/Sox2/Klf4/Myc-mediated methods.

* Discussion about selecting and purchasing a DNA sequencer, with mention of the ABI Prism 310 model used by the SoCal-DIYbio group, though they reportedly had problems with it.

* Kanzure shared a transcript from the Open Science Summit 2010 featuring an FBI representative: http://diyhpl.us/wiki/transcripts/open-science-summit-2010/ed-you/

* A user mentioned writing a paper about DIYbio and the FBI's involvement, with reference to the upcoming DIYbio Continental Congress event.

* Kanzure noted that Todd, Joe, and Matias each received $40,000 in funding from the Chilean government and were relocating there (purpose not specified in the log).

* A book review of "Biopunk" was mentioned, which referenced Kanzure (Bryan Bishop) as "the epitome of a biopunk" based on his prolific posts on DIYbio message boards.