# Summary of #hplusroadmap IRC Log (May 13, 2011)

• The Royal Society's "Science as a Public Enterprise" initiative was shared (http://royalsociety.org/policy/sape/), which aims to make scientific research more accessible to the public.

• A discussion of CAD software development occurred, with kanzure working on "lolcad," a NURBS-based solid geometry modeling tool that aims to overcome limitations of existing open-source CAD programs by supporting STEP file formats and having active maintenance.

• A paper on continuous directed evolution of biomolecules was shared (http://diyhpl.us/~bryan/papers2/bio/A%20system%20for%20the%20continuous%20directed%20evolution%20of%20biomolecules.pdf), with subsequent discussion about the limitations of "dozens of rounds per day" compared to other techniques like compartmentalized self-replication.

• There was criticism of the "protofection" project approach, suggesting that instead of just funding documentation for others to implement, the money would be better spent directly implementing the technology while documenting the process.

• GeoGebra, a GPL v2 software that provides analytical solutions to geometric constructions with 3D support, was mentioned (http://www.geogebra.org/), with comparisons to other mathematical tools like Eureqa and Sage.

• A collection of research papers on polymerase and DNA was referenced (http://diyhpl.us/~bryan/papers2/polymerase/ and http://diyhpl.us/~bryan/papers2/DNA/), in the context of discussing PacBio's sequencing technology.