# Summary of #hplusroadmap IRC Log (June 24, 2011)

* Kanzure shared synthetic biology conference abstracts from the SB5 conference, including a program book and poster index (http://sb5.biobricks.org/files/sb5-program-book-v3.pdf and http://sb5.biobricks.org/files/sb5-poster-index.pdf).

* Several interesting blog posts from the Ellington Lab were shared, including discussions on ribozymes and designer chemical weapons (http://ellingtonlab.org/blog/2011/05/22/on-ribozymes and http://ellingtonlab.org/blog/2011/04/14/on-designer-chemical-weapons).

* The SBOL (Synthetic Biology Open Language) standard was mentioned (http://www.sbolstandard.org/), with a note distinguishing it from libsbml.

* Participants discussed research on "supercharged polymerases" that can internalize into mammalian cells and demonstrate thermal/aggregation resistance.

* A discussion of RNA polymerase ribozymes highlighted work on the R18 RNA polymerase ribozyme capable of template-directed RNA synthesis up to 105 nucleotides.

* The concept of "retrosynthetic biology" was shared, describing a method that applies reversed biotransformations to design metabolic pathways for therapeutics production.

* The Spiegelman Monster, an early RNA replicase experiment, was referenced with a Wikipedia link (http://en.wikipedia.org/wiki/Spiegelman_Monster).