# Key Points from #hplusroadmap IRC Discussion

• Participants discussed bioinformatics tools development, including efforts to port Crossbow (a DNA sequence alignment tool) to Ruby and create a web service for sequence alignment, demonstrating work to make genomic analysis more accessible.

• A Nature Molecular Psychiatry paper was shared establishing that human intelligence is highly heritable and polygenic, with evidence suggesting that potentially 1,000+ genes each contribute small effects to intelligence.

• Henry Markram's Blue Brain Project was referenced with links to his presentations at the International Supercomputing Conference 2011, focusing on brain simulation techniques and progress.

• The group discussed longevity research resources, including a repository at diyhpl.us/~bryan/papers2/longevity/ and organizations like the Los Angeles Gerontology Research Group and Supercentenarian Foundation.

• A conversation about bioinformatics education included plans to create tutorials and an innovative approach to generate relational teaching materials by automatically scraping keywords from ebooks and comparing against a corpus.

• Web development tools were discussed, particularly CSS preprocessors like LESS/SASS/Compass, with recommendations for Compass (compass-style.org) and mention of a phonegap app generator for mobile development.