# Key Points from #hplusroadmap IRC Discussion

• Open-source wearable technology was highlighted through projects like SixthSense (released under GPL) and Ninja Blocks, demonstrating growing interest in connecting physical objects with digital interfaces and augmenting reality.

• Participants debated brain preservation approaches, contrasting gradual neural replacement (the "Ship of Theseus" method) with destructive scanning for mind uploading, with philosophical concerns about consciousness continuity.

• Brain-computer interfaces were discussed with consensus that invasive BCIs with electrodes directly in the motor cortex are significantly more effective than non-invasive EEG-based approaches.

• Optogenetics was examined as a promising technique for controlling neurons with light, though participants noted it requires genetic engineering of subjects, typically implemented through viral vectors.

• The conversation highlighted Ted Berger's artificial hippocampus as one of the few existing technologies aimed at replacing brain components with artificial substitutes.

• Participants discussed how genetic therapy is experiencing a resurgence after early setbacks, with improved viral vectors that avoid disrupting the genome as earlier versions did.

• Research on the rejuvenating effects of young blood on older organisms was discussed, referencing studies showing improved brain function in older mice exposed to young blood.

• Various funding mechanisms for transhumanist research were explored, including the Mprize for life extension, wealthy tech entrepreneurs, and a proposed angel investment circle of engineers pooling resources.