# Key Points from #hplusroadmap IRC Discussion (Jan 30, 2012)

• Researchers discussed bioprinting techniques for creating artificial organs by first printing vasculature patterns, then seeding cells around them, with jmil sharing work on perfusable tissues and noting that primary cells cannot survive direct printing due to high shear stresses.

• Organ bioprinting timelines were estimated at 15-20 years, with jmil mentioning a proof-of-concept for microCT to 3D-printed vasculature, while Stee| described electrohydrodynamic jet printing technology with sub-1μm precision using closed-loop control.

• A scientific study (Conboy et al., Nature 2005) was referenced showing rejuvenation effects in aged progenitor cells when connecting an old mouse to a young mouse's bloodstream, suggesting circulating factors can restore regenerative potential.

• Participants debated open access scientific publishing, with opponents claiming it would "disrupt the science industry's stability in the US" while proponents argued taxpayer-funded research should be freely available.

• Kevin Kelly's article on "undetectable technology" sparked philosophical discussion about advanced technology becoming indistinguishable from natural systems, reflecting on the future convergence of artificial and biological systems.

• The conversation included technical discussions about DLP (Digital Light Processing) technology potentially applicable to DNA synthesis, and methods for creating transistors in ultra-high vacuum environments for self-replicating lunar factories.