# Key Points from #hplusroadmap IRC Discussion

• MITx launched its first online course, 6.002x (Circuits and Electronics), marking an early milestone in MIT's online education initiative that would later influence MOOC development in higher education.

• Significant genomics discussions occurred around PacBio's DNA de novo and hybrid assembly techniques, with kanzure sharing a comprehensive 41MB compilation of DNA synthesis papers highlighting various methodologies including synthesis without base protection.

• Advanced microfluidics technology was discussed, featuring a platform with 12,870 reactors controlled by just 16 air channels, demonstrating remarkable progress in multiplex synthesis capabilities relevant to biotechnology applications.

• Participants debated phage therapy's limitations, particularly how human immune systems attack phages before they can eliminate bacteria, while acknowledging it remains promising for combating antibiotic-resistant bacteria.

• Resources shared included MiCADO (an AutoCAD plugin for microfluidics design), PCB design documentation, and the DIYbio Google Group, reflecting the community's focus on open-source tools for biohacking and citizen science.

• A nuanced discussion of fitness methodologies critically analyzed CrossFit's approach, highlighting its cross-training benefits alongside concerns about shoulder injuries, insufficient program scaling, and form issues during high-intensity workouts.