# Key Points from #hplusroadmap IRC Discussions

• Participants debated human visual perception capabilities, with many reporting sensitivity to refresh rates below 100Hz and some requiring 120Hz displays to avoid headaches, suggesting significant individual variation in visual processing.

• Future display technology was envisioned to evolve toward head-mounted displays with eye tracking that would optimize computational resources by rendering high detail only where the user is looking.

• The democratization of science faces significant barriers including prohibitively expensive equipment (like $50,000 thermocyclers) and limited access to training, with debate about whether specialized manufacturer training programs could make complex scientific tools more accessible to non-academics.

• A philosophical discussion questioned whether PhDs are necessary for meaningful scientific research, with some arguing that motivated individuals could be trained to operate complex equipment relatively quickly without advanced degrees.

• Various cognitive enhancement approaches were compared, including pharmaceutical options like modafinil, vyvanse, guanfacine, and trazodone, with participants noting their differential effects on concentration, alertness, and sleep patterns.

• A biohacking project focused on myostatin inhibition was outlined, including discussions of equipment needs, budget considerations, and challenges of testing electroporation techniques without proper animal models.

• An innovative approach to viral vector engineering was discussed, involving "2nd-generation genomes" that would express different capsid proteins depending on cell type to improve infection rates for targeted delivery.