# Key Ideas from the IRC Log

• A philosophical debate contrasted mathematical objectivity (argued to be true across all possible universes) with the view that mathematics is a human-created system based on useful axioms.

• Criticism of the LessWrong community highlighted their theoretical focus on Friendly AI without sufficient engineering progress, creating a precautionary approach that impedes practical development.

• Discussion of the "new aesthetic" movement described the convergence of glitch art, machine vision, and digital fabrication with traditional design, including examples like 3D printed dresses.

• Technical conversation about microfluidics focused on Electrowetting on Dielectric (EWOD) technology for manipulating droplets across electrical contacts using medium-high voltage on printed circuit boards.

• Participants explored developing an open-source, low-cost DNA synthesizer (targeting <$10k versus $150-200k commercial units), referencing various microfluidic synthesis techniques.

• A biohacking project was proposed to genetically modify black soldier fly larvae with termite salivary cellulase to enable conversion of newspaper into chicken feed.

• Developers discussed DIY protein purification methods using elastin-like polypeptide (ELP) tags that allow purification through precipitation rather than expensive column chromatography.

• The group critiqued the OpenPCR device's $599 price point, noting DIY heat cyclers could be built for under $100 or used professional machines could be found for $300-400.