# Key Points from Transhumanist IRC Discussion

• Participants explored transcranial direct current stimulation (tDCS) mechanisms, noting that the anode causes neural potentiation while the cathode causes dampening, with shared research showing significant temperature increases (14.68°C on scalp) at higher currents and a project on using tDCS to induce lucid dreaming.

• A novel "eyeborg" implant was discussed that enables "seeing colors through sound" by connecting to the skull with three screws to transmit sound vibrations, representing an interesting case of sensory augmentation technology.

• Users compared research organization tools, recommending Zotero for its academic publisher scrapers while lamenting the lack of effective tagging file systems for managing research papers.

• A chorded keyboard project (http://www.in10did.com/) was shared that claims to enable 30 WPM with just 10 keys, sparking discussion about typing efficiency where some users reported achieving 130-160 WPM.

• The conversation included detailed pharmacological comparisons between methamphetamine and regular amphetamine for cognitive enhancement, with arguments that methamphetamine offers better blood-brain barrier penetration resulting in higher CSF levels with fewer peripheral effects, despite prohibitive prescription costs.

• Participants debated open-source versus proprietary approaches to biotech development, with some arguing that open-source accelerates technology availability while others maintained that commercial biotech (like Histogen's regenerative medicine technology) is necessary for certain advances.