# Key Points from #hplusroadmap IRC Discussion

• Participants explored precision manufacturing technologies for biomedical applications, comparing 5-axis CNC machines with laser sintering systems (SLS/DMLS) that can achieve 20-40 micron precision, noting that different technologies are optimal at different scales.

• Advanced multi-material 3D printing was discussed, highlighting Objet printers ($43k) that can print seven different materials including transparent and high-temperature resistant options suitable for medical applications.

• A former SENS graduate student shared research on breaking down lipofuscin (age-related cellular waste) using wastewater treatment plant activated sludge, noting that similar experiments were being proposed without awareness of previous work.

• Participants debated charity efficiency, noting that of the $304 billion given to nonprofits in 2009, a more transparent, bitcoin-based charity model could potentially reduce waste and allow donors to verify how their contributions are used.

• The discussion addressed cancer research funding effectiveness, arguing that "curing cancer" is too vague since cancer encompasses many different conditions, and suggesting basic biology research might be more valuable than disease-specific approaches.

• Information was shared about an upcoming DIYbio Europe meeting in Paris, with links to registration (http://diybioeurope.eventbrite.com) and the organization's website (http://www.diybio.eu/diybio-europe-kick-off-meeting-1st-dec-paris/).