# Summary of #hplusroadmap IRC Log (Nov 21, 2012)

* Strangewarp shared experiences with nootropic combinations, noting that noopept + cognizin (citicoline) + caffeine produced a Buddha-like feeling but reduced productivity and information processing capacity, suggesting noopept should be combined with either cognizin or caffeine, but not both.

* Discussion of yerba mate revealed it contains caffeine, theobromine, and various phenolics, with participants sharing a link to research on its chemical composition (http://www.mdpi.com/1420-3049/12/3/423).

* Nmz787 shared research papers on microfluidics techniques, including "Rapid prototyping of glass-based microfluidic chips utilizing two-pass defocused CO2 laser beam method" and a paper on thermal actuation of microfluidic valves.

* Participants discussed DNA dyes for microfluidics experiments, specifically YOYO-1 DNA Dye which costs $400 for 200μL, with suggestions to start with simpler experiments using food coloring dyes.

* Fenn noted that citicoline has been shown to "elevate ACTH independently from CRH levels and to amplify the release of other HPA axis hormones," and participants discussed safe dosing of noopept (recommended under 30mg per dose to avoid liver damage).

* Kanzure shared a link to the Open Source Hardware Association's best practices (http://www.oshwa.org/sharing-best-practices/), which was criticized for being too electronics-focused and having a condescending tone.