# Summary of ##hplusroadmap IRC Log (Nov 25, 2012)

* A paper on peroxiredoxin enzyme was shared (http://www.sciencedaily.com/releases/2011/10/111031215938.htm), which appears to be related to oxidative stress and possibly circadian rhythms.

* Discussion about caloric restriction diets revealed skepticism about their effectiveness, with participants noting that recent primate studies showed no longevity benefits, contrary to earlier rodent models.

* Participants discussed oxidative and inflammatory stressors in diet, specifically identifying linoleic acid, fructose, and gliadin (and other prolamines) as known pathways for inflammation and oxidative stress.

* A participant mentioned CDPPB/MGluR5 research (Fowler et al. paper), though details weren't elaborated upon in the conversation.

* An interesting materials science concept was shared about photo-enhanced diffusion of hydrogen from hollow glass microspheres to maximize gravimetric energy density (http://ceer.alfred.edu/Research/glassspheres.html).

* Discussion of fish oil supplements revealed that not all fish oils are equivalent, with a distinction between triglyceride forms and ethyl ester forms, the latter being a purification method invented in the 1980s (http://www.ascentahealth.com/health-science/science-articles/fish-oil-triglycerides-vs-ethyl-esters-as-nature-intended).