# Key Ideas from #hplusroadmap IRC Discussions

• Participants discussed promising anti-aging compounds like Alagebrium (an AGE-breaker that showed potential in clinical trials but was discontinued due to funding issues) and debated various life extension approaches including metformin for blood sugar control, glycation endproduct breakers, DMAE, intermittent fasting, and hormone replacement therapies.

• A technical discussion on semiconductor manufacturing revealed that Moore's Law is slowing as production costs increase dramatically at 22nm and 14nm nodes, with participants noting that multilayer approaches and monolithic 3D chip fabrication (with a key ion-cut patent expiring in 2012) appear to be the primary path forward.

• The channel featured extensive debate about ADHD and other mental health conditions, with some arguing they are legitimate neurological disorders supported by fMRI studies and genetic evidence, while others claimed they are subjectively defined; several participants shared personal experiences with diagnosis and medication effectiveness.

• Participants critiqued current CAD software for 3D printing, suggesting that programs should allow design by manufacturing operation rather than pure geometry, noting that even RepRap has severe shape constraints.

• Alternative memory technologies were discussed, particularly memristors and RRAM (Resistive Random Access Memory), with Elpida's announcement of ReRAM chip development mentioned as evidence of the technology's maturation.

• The conversation included philosophical tensions between libertarian and transhumanist perspectives on free will, with one participant challenging another to locate free will in the brain, while also debating the definition of transhumanism as "a personal philosophy of technological self-improvement and accelerating returns."