# Key Points from #hplusroadmap IRC Discussion (April 5, 2013)

• Participants debated brain connectomics and uploading requirements, arguing that neuroanatomy alone is insufficient and that complete brain simulation might require mapping every protein and epigenetic profile beyond just morphological structures.

• A Science paper on "tissue-like printed material" sparked discussion about advanced tissue engineering techniques, specifically the possibility of depositing biological systems layer by layer in a vitrified state.

• Users collaborated on creating a "science defense force" to combat copyright enforcement, sharing specific IP addresses and user agent strings associated with surveillance entities that could be blocked from accessing scientific paper repositories.

• The group compared scientific journal pricing models, noting the Journal of the Electrochemical Society charged approximately $0.18 per page while Elsevier's Journal of Electroanalytical Chemistry charged about $6.28 per page despite similar impact factors.

• Bitcoin mining economics were analyzed, with participants calculating that ASIC mining offered approximately 100,000% return on electricity costs, while FPGA mining offered around 6,500% return.

• Concerns were raised about the emerging H7N9 bird flu outbreak in China, which had killed 6 people at that point, with participants sharing flu monitoring resources like newfluwiki2.com.