# Key Points from #hplusroadmap IRC Discussion (April 24, 2013)

• Cambrian Genomics' DNA synthesis technology was discussed in detail, describing their novel process of synthesizing DNA on beads, sequencing on plates, and using laser-induced forward transfer to select correctly synthesized sequences, though some participants expressed skepticism about whether this truly improved upon traditional methods.

• Organovo Holdings was highlighted for developing 3D printing techniques capable of producing functional human liver tissue samples (500 microns thick with 20 cell layers) that can produce cholesterol and liver enzymes for drug testing applications.

• Participants explored biodegradable materials for containers, recommending PLA compostable deli containers, fungi-based materials, and rice hulls, which have unique properties due to their high mineral content.

• A substantive conversation about psychedelic research referenced Rick Strassman's work on DMT and the emerging field of psychedelic genomics, with debate about the scientific validity of claims regarding psychedelics' effects on consciousness.

• Near-Infrared Hemoencephalography (NIR HEG) was discussed as a brain imaging technique, with participants noting its ability to measure blood flow but acknowledging limitations due to light scattering and the lack of proven reverse causal relationship between blood flow increase and neuronal activity.

• The environmental impact of software development was quantified through a discussion of Debian's Haskell packages, noting that rebuilding 537 packages required 48 hours and produced approximately 15kg of CO2.