# Key Points from #hplusroadmap IRC Discussion

• A debate on labor economics in biology explored how an excess of biology majors creates cheap labor for biotech startups, with counterarguments that this primarily benefits those with existing capital and industry connections rather than enabling true bootstrapping.

• The Selected Papers Network (https://github.com/cjlee112/spnet) was discussed as an initiative to improve scientific paper sharing and discussion, representing efforts to enhance open scientific collaboration.

• Participants critiqued D-Wave's quantum computing claims, noting that standard laptops running simulated annealing can outperform D-Wave's quantum computer on its native problems, referencing Scott Aaronson's analysis (http://www.scottaaronson.com/blog/?p=1400).

• A discussion on computational architectures highlighted limitations of von Neumann architecture and Turing machines, with some advocating for reduced abstraction layers and direct hardware implementation of algorithms to improve performance.

• The state of synthetic biology was criticized when someone noted that even "the most experienced person in the world" at Gibson Assembly had only performed the technique 100 times, alongside mention of Gibthon (http://gibthon.org/), an open-source Gibson Assembly design tool.

• The NIH's announcement to distance itself from the DSM-5 in favor of neurobiological explanations for cognitive disorders was highlighted as a significant shift in how mental health conditions are conceptualized and classified.

• Project Hieroglyph was discussed as an initiative to develop actionable technological roadmaps, though some participants criticized its limited scope and ambition in projects like lunar 3D printing.