# Key Points from #hplusroadmap IRC Discussions

• Participants critically analyzed the Si-elegans project (www.si-elegans.eu), arguing that its justification for using FPGAs to simulate C. elegans neurons was technically flawed, particularly regarding claims about timing precision that could be achieved with conventional computing approaches.

• A significant "brain drain" phenomenon was discussed where talented biology researchers are migrating to computer science fields, motivated by substantially higher salaries ($150-200K in CS versus $60K in biology) and fewer credential requirements.

• Scientists have developed a method to charge mobile phones using urine through microbial fuel cells (MFCs), demonstrating an innovative application of biological energy harvesting technology.

• Participants compared different computational neuroscience initiatives, contrasting the Si-elegans project unfavorably with OpenWorm, and expressing skepticism about Henry Markram's claims of simulating a human brain within ten years.

• A practical discussion occurred about sourcing laboratory equipment and materials, revealing significant price disparities for E. coli strains ($11.50 from educational suppliers versus $300+ from ATCC), highlighting cost barriers in DIY biology.

• There was mention of a potential Bitcoin-based business opportunity to manufacture medicines for rare diseases currently in shortage, referencing the FDA Drug Shortages Index as a source for identifying needed pharmaceuticals.