# Key Points from IRC Logs

• Discussions explored theoretical constraints on superintelligence, including the "Sandberg limit" which proposes that brain size is fundamentally limited by communication speeds, alongside debates about whether superintelligent AI would face unsolvable problems.

• Early transhumanist community building tactics were examined, including Eliezer Yudkowsky's approach of encouraging followers to donate significant portions of income to MIRI, which had $1.6M revenue in 2012.

• The community shared resources on genome engineering technologies (ZFN, TALEN, and CRISPR-Cas), particularly related to sickle cell disease treatment, demonstrating ongoing interest in biotechnology applications.

• Emerging enhancement technologies were discussed, including infrared contact lenses for enhanced vision capabilities and "minimum nootropics" approaches for cognitive enhancement that were documented in the DIY H+ wiki.

• Historical context about early transhumanist online communities was preserved, including the Extropians mailing list which reached 1800 emails/month pre-1993 and featured a "Hawthorne exchange" system for content quality control.

• The Allen Mouse Brain Connectivity Atlas was referenced as significant neuroscience mapping work, while CLaSH (a functional hardware description language) was shared, showing interest in alternative approaches to hardware design.

• A blog post highlighted systemic failures in scientific research funding through the case of Douglas Prasher, who pioneered GFP work but was denied funding and recognition despite his foundational contributions.