# Key Insights from Transhumanist and Technology Discussions

• Participants explored cognitive enhancement through dietary changes and nootropics, debating whether improvements in working memory tasks translate to general cognitive ability, with discussion of the neurobiological mechanisms involving the frontal cortex, parietal cortex, and basal ganglia.

• The group discussed evolutionary approaches to health science, describing the paleo diet framework as "taking shortcuts in science using anthropological norms as a null hypothesis," which enabled researchers to discover mechanisms like vitamin K2 and gluten-autoimmunity connections decades before conventional biochemistry.

• Several conversations centered on self-experimentation and personalized health approaches, with users sharing how dietary changes addressed mysterious symptoms, emphasizing measurement as key to success in health interventions, and debating how to track complex biomarkers without specialized equipment.

• Technical discussions included cryptocurrency technologies (particularly Counterparty/XCP), the challenges of creating comprehensive chemical reaction databases (most being proprietary), and the philosophical nature of technology dependency trees.

• Participants shared innovative concepts like minimalist living spaces inspired by Buckminster Fuller's "dymaxion" principles, and discussed DIY manufacturing approaches for technology bootstrapping, including the specific sequence for building foundry equipment and machine tools.

• The group explored regulatory limitations that restrict amateur technology development, with some suggesting medical tourism as a workaround for treatments like phage therapy, while others argued this only benefits those with resources.

• Educational resources were shared throughout the conversations, including Metacademy.org for AI and machine learning concepts, papers on neurofeedback for training neural areas resistant to conventional rewiring, and resources on animal cognition and training.