# Key Themes from #hplusroadmap IRC Discussions

• Participants engaged in detailed technical discussions about DNA synthesis technologies, comparing Cambrian Genomics' laser-based approach for isolating sequence-verified oligonucleotides with traditional chemistry automation and enzyme-based methods, while debating the feasibility of microfluidic DNA synthesizers.

• DIY electronics manufacturing was explored, including diamond-like carbon deposition for integrated circuits, alternative materials like titanium boride for 3D printer nozzles, and the challenges of garage-based microchip fabrication through projects like HomeCMOS.

• Browser technology limitations were a recurring theme, with users comparing memory usage across browsers (Chrome using 4GB for 326 tabs versus Firefox with 360 tabs), discussing rendering engine differences (Gecko, Webkit, Blink), and proposing alternative content organization systems using Bayesian classifiers.

• The group debated the expressive power of mathematical notation versus code, arguing that equations can represent multiple relationships simultaneously and allow for variable manipulation in ways that Turing-complete languages cannot due to the "principle of least power."

• Biotechnology initiatives were highlighted, including Craig Venter's Human Longevity Inc. ($70M funding to sequence 40,000-100,000 genomes annually) and research on functional electrical stimulation promoting neural cell proliferation in rats with cerebral infarction.

• Participants discussed aerospace technology, calculating that equatorial rocket launches save 1-1.3% of orbital velocity (significant due to the Tsiolkovsky rocket equation), and debating whether aerostats could replace satellite communications.

• The conversation touched on digital preservation efforts, with kanzure merging specialized wikis (including machinewiki and LA biohackers' wiki) into diyhpluswiki.git to prevent content loss as these resources disappear.